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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

mammalian cell systems

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Tim3 (1) Apoptosis (1) Biochemical Assay Reagents (4) Calcium Channel (1) FOXO (1) Insecticide (1) mRNA (1) Necroptosis (1) NF-κB (1) Reference Standards (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Inflammation/Immunology (3) Neurological Disease (1)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	mRNA (1) Reporter Genes (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: mTOR Programmed Cell Death 4 (PDCD4) Itk TOPK NAMPT ALCAM/CD166 GDNF Receptor BCL6 Tim3 VISTA BMI1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-174497

eGFP mRNA	mRNA	Others
eGFP mRNA expresses green fluorescent protein derived from the jellyfish Aequorea victoria. eGFP is a commonly used direct-detection reporter gene in mammalian cell culture, which produces bright green fluorescence. This product is synthesized without modified nucleosides, with a Cap1 version cap analog at the 5' end and a 100nt PolyA tail at the 3' end. It can be used as a positive reference for IVT (in vitro transcription) or LNP delivery systems.

HY-Y1365C

Fish Gelatin,suitable for cell culture	Biochemical Assay Reagents	Others
Fish Gelatin,suitable for cell culture is an essential natural biopolymer. Fish Gelatin,suitable for cell culture can be isolated from fish processing by-products, such as fish skin, scales, bones and fish maw. Fish Gelatin,suitable for cell culture has been considered as a feasible substitute for mammalian gelatin. Modified Fish gelatin shows significant promise across various industries, including nanomaterials, 3D printing, thin films, coatings, and biopharmaceuticals. Fish Gelatin,suitable for cell culture can be used for cell culture .

HY-W030778

Nitrilotriacetic acid 1 Publications Verification Triglycollamic acid	Biochemical Assay Reagents	Others
Nitrilotriacetic acid is an orally active chelating agent for metal ions. Nitrilotriacetic acid is an aminotricarboxylic acid that can sequester metal ions as water soluble complexes. Nitrilotriacetic acid reacts with strong oxidizing agents such as hypochlorite, chlorine, ozone, or oxygen in the presence of palladium/carbon catalyst. Nitrilotriacetic acid interacts with solid phases such as cell membranes and bone matrices in the mammalian system. Nitrilotriacetic acid is classified as an epigenetic rodent carcinogen .

HY-W259668

Homopropargylglycine	Biochemical Assay Reagents	Others
Homopropargylglycine is a Methionine (HY-13694) analogue. Homopropargylglycine is incorporated at a suitable rate into newly synthesized proteins in a variety of systems, including mammalian cell culture. Homopropargylglycine can be used to identify old and new protein populations . Homopropargylglycine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P5142

ω-Hexatoxin-Hv1a ω-ACTX-Hv1; ω-Atracotoxin-HV1	Insecticide Calcium Channel Apoptosis Necroptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology
ω-Hexatoxin-Hv1a (ω-ACTX-Hv1; ω-Atracotoxin-HV1) is an orally active insecticidal neurotoxin containing an inhibitor cystine knot motif and a selective calcium channel inhibitor. ω-Hexatoxin-Hv1a blocks L-type voltage-dependent Ca ²⁺ channels and reduces intracellular calcium ion concentration, thereby decreasing apoptosis, necroptosis and oxidative stress, and promoting cell recovery and energy level elevation. ω-Hexatoxin-Hv1a causes larval paralysis and death by impairing neurotransmission in the central nervous system of insects. It shows high injectable toxicity against insects of multiple orders, but exhibits weak oral toxicity. ω-Hexatoxin-Hv1a is widely applicable to studies related to ischemia-reperfusion injury, atopic dermatitis, and ischemic injury of cardiomyocytes and neurons .

HY-W030778R

Nitrilotriacetic acid (Standard) Triglycollamic acid (Standard)	Biochemical Assay Reagents Reference Standards	Others
Nitrilotriacetic acid (Standard) is the analytical standard of Nitrilotriacetic acid. This product is intended for research and analytical applications. Nitrilotriacetic acid is an orally active chelating agent for metal ions. Nitrilotriacetic acid is an aminotricarboxylic acid that can sequester metal ions as water soluble complexes. Nitrilotriacetic acid reacts with strong oxidizing agents such as hypochlorite, chlorine, ozone, or oxygen in the presence of palladium/carbon catalyst. Nitrilotriacetic acid interacts with solid phases such as cell membranes and bone matrices in the mammalian system. Nitrilotriacetic acid is classified as an epigenetic rodent carcinogen .

HY-163982

FOXJ1 agonist 1	NF-κB FOXO	Inflammation/Immunology
FOXJ1 agonist 1 (compound 16c) is an orally effective small molecule that can effectively enhance the expression of *FOXJ1. Foxj1-IN-1 acts on the mammalian* airway system composed of multiciliated cells (MCC) to prevent the development and onset of chronic obstructive pulmonary disease (COPD). Foxj1-IN-1 can induce the production of motile cilia in the respiratory system of zebrafish and mammals, and inhibit elastase-induced COPD mouse models. Foxj1-IN-1 has good liver microsomal stability, in vivo PK curve and AUC; it has no significant inhibition of CYP and hERG, and does not have significant cytotoxicity .

HY-P992342

DCB-8	Tim3	Cancer
DCB-8 is a specific inhibitor targeting human TIM-3. DCB-8 regulates T cell function, enhances cytokine secretion, and inhibits tumor growth in disease animal models. DCB-8 can be used for cancer research .

Cat. No.	Product Name	Type

HY-Y1365C

Fish Gelatin,suitable for cell culture	Biochemical Assay Reagents
Fish Gelatin,suitable for cell culture is an essential natural biopolymer. Fish Gelatin,suitable for cell culture can be isolated from fish processing by-products, such as fish skin, scales, bones and fish maw. Fish Gelatin,suitable for cell culture has been considered as a feasible substitute for mammalian gelatin. Modified Fish gelatin shows significant promise across various industries, including nanomaterials, 3D printing, thin films, coatings, and biopharmaceuticals. Fish Gelatin,suitable for cell culture can be used for cell culture .

Fish Gelatin,suitable for cell culture

Biochemical Assay Reagents

Fish Gelatin,suitable for cell culture is an essential natural biopolymer. Fish Gelatin,suitable for cell culture can be isolated from fish processing by-products, such as fish skin, scales, bones and fish maw. Fish Gelatin,suitable for cell culture has been considered as a feasible substitute for mammalian gelatin. Modified Fish gelatin shows significant promise across various industries, including nanomaterials, 3D printing, thin films, coatings, and biopharmaceuticals. Fish Gelatin,suitable for cell culture can be used for cell culture .

HY-W782399

CORM-A1 Sodium boranocarbonate	Biochemical Assay Reagents
CORM-A1 (Sodium boranocarbonate) is a water-soluble carbon monoxide (CO) releasing molecule that facilitates the investigation of CO's impact on cellular systems. As CO is generated from heme degradation by the enzyme heme oxygenase, it serves as a crucial gaseous signaling mediator in mammalian cells. CORM-A1 not only exhibits anti-oxidant and anti-inflammatory properties but also regulates CO release in a manner dependent on pH and temperature, promoting mild vasorelaxation and hypotension. Furthermore, CORM-A1 has been shown to provide cytoprotection in primary cultures of astrocytes under oxidative stress while also enhancing autophagy due to its boron-containing composition.

CORM-A1

Sodium boranocarbonate

Biochemical Assay Reagents

CORM-A1 (Sodium boranocarbonate) is a water-soluble carbon monoxide (CO) releasing molecule that facilitates the investigation of CO's impact on cellular systems. As CO is generated from heme degradation by the enzyme heme oxygenase, it serves as a crucial gaseous signaling mediator in mammalian cells. CORM-A1 not only exhibits anti-oxidant and anti-inflammatory properties but also regulates CO release in a manner dependent on pH and temperature, promoting mild vasorelaxation and hypotension. Furthermore, CORM-A1 has been shown to provide cytoprotection in primary cultures of astrocytes under oxidative stress while also enhancing autophagy due to its boron-containing composition.

Cat. No.	Product Name	Target	Research Area

HY-P5142

ω-Hexatoxin-Hv1a ω-ACTX-Hv1; ω-Atracotoxin-HV1	Insecticide Calcium Channel Apoptosis Necroptosis	Cardiovascular Disease Neurological Disease Inflammation/Immunology
ω-Hexatoxin-Hv1a (ω-ACTX-Hv1; ω-Atracotoxin-HV1) is an orally active insecticidal neurotoxin containing an inhibitor cystine knot motif and a selective calcium channel inhibitor. ω-Hexatoxin-Hv1a blocks L-type voltage-dependent Ca ²⁺ channels and reduces intracellular calcium ion concentration, thereby decreasing apoptosis, necroptosis and oxidative stress, and promoting cell recovery and energy level elevation. ω-Hexatoxin-Hv1a causes larval paralysis and death by impairing neurotransmission in the central nervous system of insects. It shows high injectable toxicity against insects of multiple orders, but exhibits weak oral toxicity. ω-Hexatoxin-Hv1a is widely applicable to studies related to ischemia-reperfusion injury, atopic dermatitis, and ischemic injury of cardiomyocytes and neurons .

HY-P4084A

KLA seq acetate	Peptides	Others
KLA seq acetate is a cell membrane-penetrating α-helical amphipathic model peptide. KLA seq acetate conjugates peptide nucleic acids (PNAs) for delivery to mammalian cells. KLA seq acetate covalently links targeted mRNA and fluorescein to form a delivery system that has low re-export and is less resistant to serum effects .

Cat. No.	Product Name

HY-K0217

Anti-Flag Affinity Gel 5 Publications Verification
MCE Anti-Flag Affinity Gel is used for immunoprecipitation (IP) or protein purification of specific Flag-tagged (DYKDDDDK) proteins expressed in bacterial and mammalian cells and in vitro expression systems.

HY-K0222

Anti-GST Magnetic Beads 20+ Cited Publications
MCE Anti-GST Magnetic Beads are used for immunoprecipitation (IP) of specific GST-tagged proteins expressed in bacterial and mammalian cells and in vitro expression systems. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-K0209

Anti-His Magnetic Beads 20+ Cited Publications
MCE Anti-His Magnetic Beads are used for immunoprecipitation (IP) of specific His-tagged proteins expressed in bacterial and mammalian cells and in vitro expression systems. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-K0201

Anti-HA Magnetic Beads 145+ Cited Publications
MCE Anti-HA Magnetic Beads are used for immunoprecipitation (IP) of specific HA-tagged proteins expressed in bacterial and mammalian cells and in vitro expression systems.The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-K0206

Anti-c-Myc Magnetic Beads 75+ Cited Publications
MCE Anti-c-Myc Magnetic Beads are used for immunoprecipitation (IP) of specific c-Myc-tagged proteins expressed in bacterial and mammalian cells and in vitro expression systems. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-K0201A

Anti-HA Magnetic Beads (1 μm) 4 Publications Verification
MCE Anti-HA Magnetic Beads (1 μm) are used for immunoprecipitation (IP) of specific HA-tagged proteins expressed in bacterial and mammalian cells andin vitro expression systems. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-K0207

Anti-Flag Magnetic Beads Maximum Cited Publications 220 Publications Verification
MCE Anti-Flag Magnetic Beads are used for immunoprecipitation (IP) of specific Flag-tagged (DYKDDDDK) proteins expressed in bacterial and mammalian cells and in vitro expression systems, and also suitable for Co-immunoprecipitation and purification of Flag-tagged protein. The 1 mL is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

Cat. No.	Product Name	Target	Research Area	Image

HY-P992342

DCB-8	Tim3	Cancer
DCB-8 is a specific inhibitor targeting human TIM-3. DCB-8 regulates T cell function, enhances cytokine secretion, and inhibits tumor growth in disease animal models. DCB-8 can be used for cancer research .

Cat. No.	Product Name		Classification

HY-W259668

Homopropargylglycine		Alkynes
Homopropargylglycine is a Methionine (HY-13694) analogue. Homopropargylglycine is incorporated at a suitable rate into newly synthesized proteins in a variety of systems, including mammalian cell culture. Homopropargylglycine can be used to identify old and new protein populations . Homopropargylglycine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-174497

eGFP mRNA		mRNA Reporter Genes
eGFP mRNA expresses green fluorescent protein derived from the jellyfish Aequorea victoria. eGFP is a commonly used direct-detection reporter gene in mammalian cell culture, which produces bright green fluorescence. This product is synthesized without modified nucleosides, with a Cap1 version cap analog at the 5' end and a 100nt PolyA tail at the 3' end. It can be used as a positive reference for IVT (in vitro transcription) or LNP delivery systems.

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