18 Results for "

melanin formation

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "melanin formation" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-Y0351
CAS No.: 103-85-5
Synonyms: Phenylthiocarbamide
Research Areas:  

Others

Phenylthiourea (Phenylthiocarbamide) is an inhibitor for phenoloxidase. Phenylthiourea inhibits enzymatic oxidation of DOPA by phenoloxidase (Ki = 0.21 μM). Phenylthiourea is an effective inhibitor for tyrosinase. Phenylthiourea can lead to graying of hair in black rats due to the interference with melanin formation .
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1
1 Cited Publications
Cat. No.: HY-W015967
CAS No.: 79-14-1
Synonyms: Hydroxyethanoic acid
Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
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Cat. No.: HY-Y0444
CAS No.: 556-02-5
D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth .
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Cat. No.: HY-107663A
CAS No.: 35240-69-8
Purity:  98.01%
Synonyms: Pro-Leu-Gly-NH2 TFA; Melanostatin TFA
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

MIF-1 TFA (Melanostatin), an endogenous brain peptide, is a potent dopamine receptor allosteric modulator. MIF-1 TFA inhibits melanin formation. MIF-1 TFA blocks the effects of opioid receptor activation to modulate the analgesic effects. MIF-1 TFA accesses from the blood to the CNS by directly crossing the blood-brain barrier (BBB) .
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Cat. No.: HY-N3518
CAS No.: 193483-95-3
Mulberroside F is one of the main bioactive constituents in mulberry (Morus alba L.) . Mulberroside F shows inhibitory effects on tyrosinase activity and on the melanin formation. Mulberroside F also exhibits superoxide scavenging activity that is involved in the protection against auto-oxidation .
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Cat. No.: HY-N1434
CAS No.: 3943-97-3
Synonyms: Methyl 4-hydroxycinnamate
Methyl p-coumarate (Methyl 4-hydroxycinnamate), an orally active esterified derivative of p-Coumaric acid (pCA), can be isolated from the flower of Trixis michuacana var longifolia. Methyl p-coumarate could inhibit the melanin formation in B16 mouse melanoma cells. Methyl p-coumarate also has strong in vitro inhibitory effect on A. alternata and other pathogens .
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Cat. No.: HY-W015967S
CAS No.: 75502-10-2
Glycolic acid-d2 is the deuterium labeled Glycolic acid. Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
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Cat. No.: HY-Y0444S2
CAS No.: 1426174-46-0
D-Tyrosine-d7 is the deuterium labeled D-Tyrosine (HY-Y0444) . D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth .
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Cat. No.: HY-107663
CAS No.: 2002-44-0
Synonyms: Pro-Leu-Gly-NH2; Melanostatin
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

MIF-1 (Melanostatin), an endogenous brain peptide, is a potent dopamine receptor allosteric modulator. MIF-1 inhibits melanin formation. MIF-1 blocks the effects of opioid receptor activation to modulate the analgesic effects. MIF-1 accesses from the blood to the CNS by directly crossing the blood-brain barrier (BBB) .
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Cat. No.: HY-W778203
CAS No.: 111389-68-5
Synonyms: Hydroxyethanoic acid-13C2
Glycolic acid- 13C2 is the 13C-labeled Glycolic acid (HY-W015967). Glycolic acid- 13C2 is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
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Cat. No.: HY-N14245
CAS No.: 178275-98-4
Melanoxazal is a Melanin biosynthesis inhibitor. Melanoxazal can inhibit melanin formation in the silkworm larva hemolymph (IC50 is 30.1 μg/mL), and also has stronger inhibitory effect against mushroom tyrosinase (IC50 is 4.2 μg/mL), but it has no antimicrobial effect .
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Cat. No.: HY-W015967R
CAS No.: 79-14-1
Synonyms: Hydroxyethanoic acid (Standard)
Glycolic acid (Standard) is the analytical standard of Glycolic acid. This product is intended for research and analytical applications. Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
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Cat. No.: HY-Y0444S1
CAS No.: 944386-47-4
D-Tyrosine-d4 is the deuterium labeled D-Tyrosine (HY-Y0444) . D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth .
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Cat. No.: HY-Y0444S
CAS No.: 1202064-22-9
D-Tyrosine-d2 is the deuterium labeled D-Tyrosine (HY-Y0444) . D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth .
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Cat. No.: HY-173428
Target:  

Fungal

Research Areas:  

Infection

Antifungal agent 130 (Compound A7) is an orally active antifungal agent. Antifungal agent 130 has good antifungal activity against Candida albicans (MIC = 0.12 ng/mL) and Cryptococcus neoformans (MIC = 0.12 ng/mL) and has excellent antivirulence effect. Antifungal agent 130 exerts its antifungal effect by disrupting the iron homeostasis of fungal cells and inducing oxidative stress damage. Antifungal agent 130 can inhibit the formation of fungal virulence factors (such as biofilm, capsule, urease and melanin). Antifungal agent 130 has good antifungal effect and can be used in the study of drug-resistant fungal infections .
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Cat. No.: HY-118392
CAS No.: 522-57-6
Synonyms: Xanthaline
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

Papaveraldine (Xanthaline) is a benzylisoquinoline alkaloid that shows antispasmodic and protective activity against histamine-induced bronchospasm in rats. Papaveraldine is an active ingredient of a hair tonic preparation that promotes melanin formation for grey hair .
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Cat. No.: HY-Y0444R
CAS No.: 556-02-5
D-Tyrosine (Standard) is the analytical standard of D-Tyrosine (HY-Y0444). This product is intended for research and analytical applications. D-Tyrosine is the D-isomer of tyrosine. D-Tyrosine negatively regulates melanin synthesis by inhibiting tyrosinase activity. D-Tyrosine inhibits biofilm formation and trigger the self-dispersal of biofilms without suppressing bacterial growth .
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Cat. No.: HY-184981
CAS No.: 2243516-99-4
Target:  

Urease Fungal

Research Areas:  

Infection

Urease-IN-24 is a cryptococcal urease inhibitor with a IC50 of 89.96 nM and a Ki of 64.3 nM. Urease-IN-24 acts as a competitive nickel-coordinating inhibitor that coordinates with the nickel center at the catalytic site of the enzyme via its carbonyl group. Urease-IN-24 reduces the capsule thickness of Cryptococcus neoformans and Cryptococcus gattii, increases cell membrane permeability, and inhibits melanin production. Urease-IN-24 exhibits fungicidal activity against Cryptococcus species. Urease-IN-24 can be used in the research of cryptococcosis .
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