3 Results for "

migraine attacks

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "migraine attacks" in MCE Product Catalog:

Cat. No.: HY-B1658
CAS No.: 158747-02-5
Synonyms: (R)-Frovatriptan; SB 209509; VML 251
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease

Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura .
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Cat. No.: HY-B1658S
Synonyms: (R)-Frovatriptan-d3 hydrochloride; SB 209509-d3 hydrochloride; VML 251-d3 hydrochloride
Frovatriptan-d3 (hydrochloride) is the deuterium labeled Frovatriptan . Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura .
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Cat. No.: HY-P12136
CAS No.: 1966181-14-5
Synonyms: FE 205030
Target:  

CGRP Receptor

Research Areas:  

Neurological Disease

Fonagepant (FE 205030) is a calcitonin gene-related peptide (CGRP) receptor antagonist with an IC50 of 0.2 nM. Fonagepant selectively blocks CGRP receptor activity, inhibits CGRP-induced vasodilation, attenuates capsaicin-induced increase in skin blood flow, and blocks CGRP-induced vasodilation in isolated human mesenteric resistance arteries. Fonagepant can be used in studies related to acute migraine attacks .
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