4 Results for "

normal melanocytes

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "normal melanocytes" in MCE Product Catalog:

Cat. No.: HY-P2506
CAS No.: 212370-36-0
Synonyms: Mgp100 (25-33)
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Gp100 (25-33), mouse sequence is found in residues 25 to 33 of the mouse self/tumor antigen glycoprotein (mgp100). Mgp100 is an enzyme involved in pigment synthesis, and the epitope fragment is expressed in both normal melanocytes and melanoma cells .
loading...
    loading...
Cat. No.: HY-P2506A
Synonyms: Mgp100 (25-33) TFA
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Gp100 (25-33), mouse TFA sequence is found in residues 25 to 33 of the mouse self/tumor antigen glycoprotein (mgp100). Mgp100 is an enzyme involved in pigment synthesis, and the epitope fragment is expressed in both normal melanocytes and melanoma cells .
loading...
    loading...
Cat. No.: HY-157010
CAS No.: 1365531-21-0
Target:  

Tyrosinase PKA

Research Areas:  

Others

AP736 is a potent tyrosinase inhibitor (IC50 = 0.9 μM) with anti-melanogenesis activity in normal human melanocytes (IC50 = 0.11 μM). AP736 suppresses the expression of tyrosinase and TRP-1/2 by inhibiting the cAMP-PKA-CREB signalling axis, leading to reduced microphthalmia-associated transcription factor (MITF) transcripts and proteins. AP736 can be used for melanogenesis and hyperpigmentation research .
loading...
    loading...
Cat. No.: HY-D3141
DR probe is a "dual-key-and-lock" fluorescent probe designed based on the Resorufin (HY-123533) scaffold (Ex/Em = 647 nm/663-738 nm). DR probe can be sequentially activated by hydrogen peroxide to form the intermediate SR, which acts as a tyrosinase substrate to trigger a fluorescence turn-on signal. DR probe can distinguish normal melanocytes from melanoma cells. DR probe supports cell imaging and can be applied to mouse melanoma models to achieve melanoma diagnosis with higher accuracy and lower false-positive rates. DR probe is applicable to relevant research on melanoma .
loading...
    loading...