2 Results for "

orthotopic liver tumor model

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "orthotopic liver tumor model" in MCE Product Catalog:

Cat. No.: HY-139418
CAS No.: 1198085-23-2
Target:  

FXR

Research Areas:  

Cancer

PX20350 is a FXR agonist with EC50s of 83 and 10 nM for mFXR and hFXR, respectively. PX20350 significantly induces NDRG2 mRNA expression. PX20350 potently reduces liver tumor cells (SK-GI-18 cells) growth and metastasis, and has anti-tumorigenic activity in orthotopic xenograft mouse models .
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Cat. No.: HY-P11618
Target:  

Glycoprotein VI

Research Areas:  

Cancer

10P3Me is a Glypican-3 (GPC3)-targeting probe with a Ka of 93.8 nM for the human target. 10P3Me exhibits high binding affinity to GPC3, targets GPC3-positive cells, and serves as an agent for PET imaging. 10P3Me selectively accumulates in GPC3-positive tumor tissues, including subcutaneous xenograft models and orthotopic HepG2-LUC liver cancer models, to achieve precise localization of lesions .
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