10 Results for "

penetrating skin

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "penetrating skin" in MCE Product Catalog:

3
SPACE peptide
SPACE peptide
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3 Cited Publications
Cat. No.: HY-P0123
CAS No.: 1621717-95-0
Target:  

Inhibitory Antibodies

Research Areas:  

Others

SPACE peptide is a skin penetrating peptide (SPPs). SPACE peptide can enhance topical delivery of a macromolecule, hyaluronic acid .
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Petunidin-3-O-glucoside chloride
Petunidin-3-O-glucoside chloride
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1 Cited Publications
Cat. No.: HY-N7832
CAS No.: 6988-81-4
Category:  

Anthocyans Flavonoids Metabolic Disease Myrtaceae Phenols Polyphenols Rhodomyrtus tomentosa Plants Disease Research Fields

Target:  

Tyrosinase Glycosidase Apoptosis PI3K Akt ERK Reactive Oxygen Species (ROS) MDM-2/p53

Petunidin-3-O-glucoside chloride is a blood-brain barrier-penetrating tyrosinase inhibitor with an IC50 of 10.3 μM and a Ki of 9.0 μM. Petunidin-3-O-glucoside also acts as an α-glucosidase inhibitor with an IC50 of 218.2 µM. Petunidin-3-O-glucoside chloride inhibits the SIRT3/p53-mediated mitochondrial pathway and the PI3K/Akt-ERK pathway, suppresses glycolysis, and induces cell apoptosis. Petunidin-3-O-glucoside chloride scavenges ROS to exert antioxidant activity. It can be used in research related to glioblastoma multiforme, skin anti-aging and whitening, as well as obesity .
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PXS-6302 hydrochloride
PXS-6302 hydrochloride
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Cat. No.: HY-151499A
CAS No.: 2584947-79-3
Purity:  99.83%
Target:  

Monoamine Oxidase

Research Areas:  

Inflammation/Immunology

PXS-6302 hydrochloride is an irreversible lysyl oxidase inhibitor with IC50s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 hydrochloride has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance .
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PXS-6302
PXS-6302
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Cat. No.: HY-151499
CAS No.: 2584947-54-4
Target:  

Monoamine Oxidase

Research Areas:  

Others

PXS-6302 is an irreversible lysyl oxidase inhibitor with IC50s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance .
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PXS-4787 hydrochloride
PXS-4787 hydrochloride
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Cat. No.: HY-151498A
CAS No.: 2409964-40-3
Purity:  99.71%
Target:  

Monoamine Oxidase

Research Areas:  

Others

PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 hydrochloride inhibits LOX with IC50s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively. PXS-4787 hydrochloride reduces deposition and crosslinking of collagen I secreted by human fibroblasts .
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Low molecular weight protamine
Low molecular weight protamine
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Cat. No.: HY-P5107
CAS No.: 121052-30-0
Synonyms: LMWP; TDSP5
Target:  

VEGFR

Research Areas:  

Cancer

Low molecular weight protamine (LMWP;TDSP5) is a truncated arginine-rich protamine peptide, as well as a heparin/low-molecular-weight heparin antidote and a cell-penetrating delivery carrier. Low molecular weight protamine neutralizes heparin-induced anticoagulant activities, including aPTT, anti-Xa and anti-IIa activities, and also neutralizes anti-Xa activity of commercially available low-molecular-weight heparin preparations. Low molecular weight protamine translocates across mammalian cell membranes, delivers conjugated impermeable molecules across tumor tissues, enhances skin permeability of conjugated epidermal growth factor, and accelerates wound healing when conjugated with epidermal growth factor. Low molecular weight protamine retains the in vitro cell proliferation activity of conjugated EGF, and also enables site-specific conjugation with peptides or proteins via genetic recombination. Low molecular weight protamine can be used in studies related to colon adenocarcinoma, skin wounds and diabetic skin wounds .
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PXS-4787
PXS-4787
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Cat. No.: HY-151498
CAS No.: 2409963-50-2
Target:  

Monoamine Oxidase

Research Areas:  

Others

PXS-4787 is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 inhibits LOX with IC50s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively .
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Low molecular weight protamine acetate
Low molecular weight protamine acetate
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Cat. No.: HY-P5107A
Synonyms: LMWP acetate; TDSP5 acetate
Target:  

VEGFR

Research Areas:  

Cancer

Low molecular weight protamine acetate (LMWP acetate;TDSP5 acetate) is a truncated arginine-rich protamine peptide, which also acts as an antidote for heparin/low molecular weight heparin and a cell-penetrating delivery vector. Low molecular weight protamine acetate neutralizes heparin-induced anticoagulant activities, including aPTT, anti-Xa and anti-IIa activities. Low molecular weight protamine acetate translocates across mammalian cell membranes, delivers conjugated impermeable molecules through tumor tissues, enhances the skin permeability of conjugated epidermal growth factor, and accelerates wound healing when conjugated with epidermal growth factor. Low molecular weight protamine acetate retains the in vitro cell proliferation activity of conjugated EGF, and also enables site-specific conjugation with peptides or proteins via genetic recombination. Low molecular weight protamine acetate can be used in studies related to colon cancer, skin wounds and diabetic skin wounds .
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Petunidin-3-O-glucoside chloride (Standard)
Petunidin-3-O-glucoside chloride (Standard)
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Cat. No.: HY-N7832R
CAS No.: 6988-81-4
Category:  

Anthocyans Flavonoids Microorganisms Myrtaceae Phenols Polyphenols Rhodomyrtus tomentosa Plants

Target:  

Reference Standards Tyrosinase Glycosidase Apoptosis PI3K Akt ERK Reactive Oxygen Species (ROS) MDM-2/p53

Petunidin-3-O-glucoside chloride (Standard) is the analytical standard of Petunidin-3-O-glucoside chloride (HY-N7832). This product is intended for research and analytical applications. Petunidin-3-O-glucoside chloride is a blood-brain barrier-penetrating tyrosinase inhibitor with an IC50 of 10.3 μM and a Ki of 9.0 μM. Petunidin-3-O-glucoside also acts as an α-glucosidase inhibitor with an IC50 of 218.2 µM. Petunidin-3-O-glucoside chloride inhibits the SIRT3/p53-mediated mitochondrial pathway and the PI3K/Akt-ERK pathway, suppresses glycolysis, and induces cell apoptosis. Petunidin-3-O-glucoside chloride scavenges ROS to exert antioxidant activity. It can be used in research related to glioblastoma multiforme, skin anti-aging and whitening, as well as obesity .
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YARA peptide
YARA peptide
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Cat. No.: HY-P10796
Target:  

MAPKAPK2 (MK2)

Research Areas:  

Inflammation/Immunology

YARA peptide, a cell-penetrating peptide, is a MK2 inhibitor. YARA-loaded nanoparticles decreases the levels of inflammatory cytokines (IL-1β, IL-6, and TNF-α) in an ex vivo skin culture model. YARA peptide is promising for research of atopic dermatitis (AD) .
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