2409964-40-3

PXS-4787 hydrochloride Chemical Structure
2409964-40-3

Chemical Structure

PXS-4787 hydrochloride

  • No. CAS: 2409964-40-3
  • Formula:C10H13ClFNO2S
  • Molecular Weight:265.73

SMILES: NC/C=C(CS(=O)(C1=CC=CC=C1)=O)\F.Cl

Biological Activity: PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 hydrochloride inhibits LOX with IC50s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively. PXS-4787 hydrochloride reduces deposition and crosslinking of collagen I secreted by human fibroblasts[1].

Referencia número Nombre del producto Pureza Descripciòn Pricing
HY-151498A 		PXS-4787 hydrochloride 99.71% PXS-4787 hydrochloride is a specific and effective pan-LOX (lysyl oxidase) inhibitor for abolishing lysyl oxidase activity. PXS-4787 hydrochloride inhibits LOX with IC50s of 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), 0.2 μM (rh LOXL4), respectively. PXS-4787 hydrochloride reduces deposition and crosslinking of collagen I secreted by human fibroblasts.
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