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Results for "

polynucleotide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (2) DNA Alkylator/Crosslinker (1) DNA/RNA Synthesis (5) Liposome (3) Phosphatase (1) Phosphorylase (1) Xanthine Oxidase (1)
By Research Areas:	Cancer (3) Infection (1) Metabolic Disease (3)
Oligonucleotides:	Nucleotide Analogs (1) Cationic Lipids (4) Adenine Nucleotide (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0178

1-Ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride 10+ Cited Publications	Biochemical Assay Reagents	Others
1-Ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification .

HY-137817

BCH001	DNA/RNA Synthesis	Metabolic Disease
BCH001, a quinoline derivative, is a specific PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in dyskeratosis congenita (DC) induced pluripotent stem cells. BCH001 shows no inhibition of poly(A)-specific ribonuclease (PARN) or several other canonical and non-canonical polynucleotide polymerases. BCH001 is used to regulate aging .

HY-131920A

Poly(U) potassium Polyuridylic acid potassium	DNA/RNA Synthesis	Others
Polyuridylic acid potassium is a polynucleotide. In protein synthesis systems based on active mammalian ribosomes, Polyuridylic acid potassium acts as a specific messenger to induce the biosynthesis of polyphenylalanine, with no effect on the incorporation of non-phenylalanine amino acids. Polyuridylic acid potassium serves as a template to promote the non-enzymatic synthesis of oligoadenylates .

HY-100683

A12B4C3	Phosphatase	Cancer
A12B4C3 is a potent *human polynucleotide* kinase/phosphatase (hPNKP) inhibitor with an IC₅₀** value of 0.06 μM. A12B4C3 has antiproliferative activity against cancer cells. A12B4C3 can also enhance the radiosensitivity of certain cancer cells .

HY-W250124

Ribonucleic acid (yeast) RNA (yeast)	DNA/RNA Synthesis	Others
Ribonucleic acid (RNA) (yeast) is a ribonucleic acid isolated from yeast, characterized as a polynucleotide containing primary and secondary phosphate groups, amino groups, and purine-pyrimidine hydroxyl groups per 4 corrected phosphorus atoms. Ribonucleic acid (yeast) is widely used in scientific research as a substrate for nuclease detection, a carrier in ethanol precipitation processes, and a standard control for molecular biology techniques .

HY-W010854

2'-Deoxyadenosine 5'-di-phos-phate disodium dADP disodium	DNA/RNA Synthesis	Others
2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes .

HY-W008550

8-Azaadenine	Xanthine Oxidase	Metabolic Disease Cancer
8-Azaadenine is an inhibitor of Xanthine Oxidase with an IC₅₀ of 0.54 μM and a K_i of 0.66 μM. 8-Azaadenine can be produced via the metabolism of 8-Azaadenosine (HY-115686) and incorporated into polynucleotide chains together with 8-Azaguanine (HY-B1468) to affect purine metabolism. 8-Azaadenine can be used in the study of cancer .

HY-P2844

Polynucleotide kinase	DNA/RNA Synthesis	Metabolic Disease
Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini .

HY-W541025

Deoxyribonucleic acid	Biochemical Assay Reagents	Others
Deoxyribonucleic acid is a polymer formed by two polynucleotide chains twisted around each other to form a double-helix structure. Deoxyribonucleic acid exists in all dividing cells and is a fundamental component of chromosomes .

HY-153137

Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate 304O13	Liposome	Cancer
Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate is a biodegradable lipid prepared by the conjugate addition of alkylamines to acrylates. Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate can be used in various drug delivery systems to deliver polynucleotides, siRNA for example .

HY-156936

RCB-02-4-8	Liposome	Others
RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .

HY-151510

A2-Iso5-4DC19	Liposome	Others
A2-Iso5-4DC19 is a lipidoid compound. A2-Iso5-4DC19 is an effective carrier for the delivery of an agent such as a polynucleotide to a cell .

HY-114582

Lexitropsin	DNA Alkylator/Crosslinker	Others
Lexitropsin is a netropsin derivative which is determined the binding and specificity properties in interaction with DNA and synthetic polynucleotides .

HY-W552525

Deoxyadenosine diphosphate sodium	Phosphorylase	Infection
Deoxyadenosine diphosphate sodium is a nucleoside diphosphate, in which the nucleoside is deoxyadenosine. Deoxyadenosine diphosphate sodium participates in DNA synthesis and repair. Deoxyadenosine diphosphate sodium acts as the inhibitor of polynucleotide phosphorylase, interfers with the polymerization of ADP and CDP .

Cat. No.	Product Name	Type

HY-D0178

1-Ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride 10+ Cited Publications	Biochemical Assay Reagents
1-Ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification .

1-Ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride

10+ Cited Publications

Biochemical Assay Reagents

1-Ethyl-(3-dimethylaminopropyl)carbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification .

HY-131920A

Poly(U) potassium Polyuridylic acid potassium	Biochemical Assay Reagents
Polyuridylic acid potassium is a polynucleotide. In protein synthesis systems based on active mammalian ribosomes, Polyuridylic acid potassium acts as a specific messenger to induce the biosynthesis of polyphenylalanine, with no effect on the incorporation of non-phenylalanine amino acids. Polyuridylic acid potassium serves as a template to promote the non-enzymatic synthesis of oligoadenylates .

Poly(U) potassium

Polyuridylic acid potassium

Biochemical Assay Reagents

Polyuridylic acid potassium is a polynucleotide. In protein synthesis systems based on active mammalian ribosomes, Polyuridylic acid potassium acts as a specific messenger to induce the biosynthesis of polyphenylalanine, with no effect on the incorporation of non-phenylalanine amino acids. Polyuridylic acid potassium serves as a template to promote the non-enzymatic synthesis of oligoadenylates .

HY-W250124

Ribonucleic acid (yeast) RNA (yeast)	Biochemical Assay Reagents
Ribonucleic acid (RNA) (yeast) is a ribonucleic acid isolated from yeast, characterized as a polynucleotide containing primary and secondary phosphate groups, amino groups, and purine-pyrimidine hydroxyl groups per 4 corrected phosphorus atoms. Ribonucleic acid (yeast) is widely used in scientific research as a substrate for nuclease detection, a carrier in ethanol precipitation processes, and a standard control for molecular biology techniques .

Ribonucleic acid (yeast)

RNA (yeast)

Biochemical Assay Reagents

Ribonucleic acid (RNA) (yeast) is a ribonucleic acid isolated from yeast, characterized as a polynucleotide containing primary and secondary phosphate groups, amino groups, and purine-pyrimidine hydroxyl groups per 4 corrected phosphorus atoms. Ribonucleic acid (yeast) is widely used in scientific research as a substrate for nuclease detection, a carrier in ethanol precipitation processes, and a standard control for molecular biology techniques .

HY-W010854

2'-Deoxyadenosine 5'-di-phos-phate disodium dADP disodium	Biochemical Assay Reagents
2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes .

HY-W541025

Deoxyribonucleic acid	Biochemical Assay Reagents
Deoxyribonucleic acid is a polymer formed by two polynucleotide chains twisted around each other to form a double-helix structure. Deoxyribonucleic acid exists in all dividing cells and is a fundamental component of chromosomes .

HY-153137

Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate 304O13	Biochemical Assay Reagents
Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate is a biodegradable lipid prepared by the conjugate addition of alkylamines to acrylates. Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate can be used in various drug delivery systems to deliver polynucleotides, siRNA for example .

HY-151510

A2-Iso5-4DC19	Biochemical Assay Reagents
A2-Iso5-4DC19 is a lipidoid compound. A2-Iso5-4DC19 is an effective carrier for the delivery of an agent such as a polynucleotide to a cell .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71620

	PNKP Protein, Human (His-SUMO) 2''(3'')-polynucleotidase; 2'(3')-polynucleotidase; Bifunctional polynucleotide phosphatase/kinase; DEM 1; DEM1; polynucleotide kinase-3''-phosphatase	Human	E. coli
	PNKP protein plays a key role in DNA damage repair through NHEJ and BER pathways. Its dual catalytic activity includes removal of the 3'-phosphate group from the DNA backbone and phosphorylation of the 5'-hydroxyl group, ensuring compatibility of DNA ends during extension and ligation. PNKP Protein, Human (His-SUMO) is the recombinant human-derived PNKP protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

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HY-P86815

	CLP1 Antibody (YA6508) ATP/GTP binding protein antibody; Cleavage and polyadenylation factor I subunit 1 antibody; CLP 1 antibody; clp1 antibody; CLP1 cleavage and polyadenylation factor I subunit homolog antibody; CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae) antibody; CLP1, yeast, homolog of antibody; CLP1_HUMAN antibody; hClp1 antibody; Homolog of yeast CFIA subunit Clp1p antibody; ATP/GTP binding protein antibody; Cleavage and polyadenylation factor I subunit 1 antibody; CLP 1 antibody; clp1 antibody; CLP1 cleavage and polyadenylation factor I subunit homolog antibody; CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae) antibody; CLP1, yeast, homolog of antibody; CLP1_HUMAN antibody; hClp1 antibody; Homolog of yeast CFIA subunit Clp1p antibody; Polyadenylation factor Clp1 antibody; polynucleotide kinase Clp1 antibody; Polyribonucleotide 5' hydroxyl kinase Clp1 antibody; Polyribonucleotide 5''-hydroxyl-kinase Clp1 antibody; Pre mRNA cleavage complex II protein Clp1 antibody; Pre-mRNA cleavage complex II protein Clp1 antibody;	WB, IHC-P, FC	Human, Mouse, Rat
	CLP1 Antibody (YA6508) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CLP1.

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Cat. No.	Product Name		Classification

HY-W010854

2'-Deoxyadenosine 5'-di-phos-phate disodium dADP disodium		Nucleotide Analogs Adenine Nucleotide
2'-Deoxyadenosine 5'-di-phos-phate disodium (dADP disodium) is an inhibitor of bacterial poly(A) polymerase. It can be used to synthesize deoxyadenosine oligonucleotides with Escherichia coli polynucleotide phosphorylase and other enzymes .

HY-153137

Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate 304O13		Cationic Lipids
Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate is a biodegradable lipid prepared by the conjugate addition of alkylamines to acrylates. Tri-N-tridecyl 3-(ethyl(methyl)amino)propanoate can be used in various drug delivery systems to deliver polynucleotides, siRNA for example .

HY-156936

RCB-02-4-8		Cationic Lipids
RCB-02-4-8 is an ionizable cationic lipid that is used to form lipid nanoparticles (LNPs) to deliver mRNA. RCB-02-4-8 can improve the efficiency of lung transfection in mice .

HY-151510

A2-Iso5-4DC19		Cationic Lipids
A2-Iso5-4DC19 is a lipidoid compound. A2-Iso5-4DC19 is an effective carrier for the delivery of an agent such as a polynucleotide to a cell .

HY-160582

MR-2-93-3 RML-1		Cationic Lipids
MR-2-93-3 is a long-chain fatty acid that can be used to deliver polynucleotides .

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