54 Results for "

quorum sensing signal

" in MedChemExpress (MCE) Product Catalog:
Products (54)

54 Results for "quorum sensing signal" in MCE Product Catalog:

8
8 Publications Verification
Cat. No.: HY-P1934
CAS No.: 14705-60-3
Synonyms: Cyclo(phenylalanylprolyl); A-64863
Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) is a quorum-sensing molecule of Vibrio vulnificus that specifically interacts with RIG-I, inhibiting RIG-I polyubiquitination, suppressing IRF-3 activation, and reducing type I interferon production. Cyclo(Phe-Pro) enhances susceptibility to HCV and influenza virus and also alleviates plant aluminum toxicity stress. The mechanism of Cyclo(Phe-Pro) involves the regulation of host immune signaling pathways, bacterial virulence gene expression, and plant antioxidant systems, making it a promising candidate for research in viral infections, bacterial virulence regulation, and agricultural stress resistance .
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2
2 Cited Publications
Cat. No.: HY-114544A
CAS No.: 168982-69-2
Purity:  ≥98.0%
Synonyms: OdDHL
N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex [2].Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells .
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2
2 Cited Publications
Cat. No.: HY-128200
CAS No.: 108985-27-9
Purity:  99.84%
Synonyms: PQS
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

Pseudomonas quinolone signal (PQS) is a quorum-sensing signaling molecule produced by Pseudomonas aeruginosa. The synthesis of Pseudomonas quinolone signal relies on the las quorum-sensing system, and its biological activity is associated with the rhl system. Pseudomonas quinolone signal regulates the expression of the virulence gene lasB. Additionally, Pseudomonas quinolone signal plays roles in iron acquisition, cytotoxicity, outer-membrane vesicle biogenesis, and host immune modulation .
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2
2 Cited Publications
Cat. No.: HY-B0914
CAS No.: 112-38-9
Synonyms: Undecylenic acid
10-Undecenoic acid (Undecylenic acid) is an antifungal agent. 10-Undecenoic acid inhibits oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid has neuroprotective effects. 10-Undecenoic acid has anticancer effects on a variety of tumors. 10-Undecenoic acid inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .
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2
2 Cited Publications
Cat. No.: HY-B0914A
CAS No.: 557-08-4
Synonyms: Zinc undecylenate
10-Undecenoic acid zinc salt (Undecylenic acid zinc salt) is an antifungal agent. 10-Undecenoic acid zinc salt inhibits oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid zinc salt has neuroprotective effects. 10-Undecenoic acid zinc salt has anticancer effects on a variety of tumors. 10-Undecenoic acid zinc salt inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid zinc salt inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .
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1
1 Cited Publications
Cat. No.: HY-118697
CAS No.: 137173-46-7
Purity:  ≥98.0%
Synonyms: C12-HSL
Target:  

Bacterial

Research Areas:  

Infection

N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule. N-dodecanoyl-L-Homoserine lactone (C12-HSL) aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
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Cat. No.: HY-P1940
CAS No.: 4549-02-4
Synonyms: Cyclo(Tyr-Pro)
Maculosin (Cyclo (Tyr-Pro)) is a host-specific phytotoxin for spotted knapweed from Alternaria alternata. Maculosin is a quorum-sensing molecule involved in cell-cell communication. Maculosin also acts as a signaling molecule regulating virulence gene expression. Maculosin shows antimicrobial, antifungal, antioxidant and anti-cancer properties .Maculosin (Cyclo (Tyr-Pro)) is a host-specific phytotoxin for spotted knapweed from Alternaria alternata. Maculosin is a quorum-sensing molecule involved in cell-cell communication. Maculosin also acts as a signaling molecule regulating virulence gene expression. Maculosin shows antimicrobial, antifungal, antioxidant and anti-cancer properties .
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Cat. No.: HY-133685
CAS No.: 147852-83-3
Purity:  98.82%
Synonyms: C6-HSL
Target:  

Bacterial

Research Areas:  

Infection Metabolic Disease

N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). N-hexanoyl-L-homoserine lactone is also a mediator of bacterial quorum-sensing regulation. N-hexanoyl-L-homoserine lactone promotes lipid accumulation in algae. AHL is an intercellular communication signal molecule in the quorum sensing system of Gram-negative bacteria and a medium for mediating information exchange between eukaryotic plants and prokaryotic bacteria. AHL can affect bacteria activities, such as biofilm formation, pigment synthesis, and antibiotic synthesis .
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Cat. No.: HY-W008806
CAS No.: 143537-62-6
Synonyms: OHHL; N-(3-Oxohexanoyl)homoserine lactone
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

N-(3-Oxohexanoyl)-L-homoserine lactone (OHHL; N-(3-Oxohexanoyl)homoserine lactone) is a specific agonist of LuxR-type transcription factor CarR with a Kd of 1.8 μM. N-(3-Oxohexanoyl)-L-homoserine lactone activates CarR by inducing protein multimerization, promoting its binding to target DNA sequences in the carR-carA intergenic region, thereby upregulating the transcription of carbapenem biosynthesis genes. N-(3-Oxohexanoyl)-L-homoserine lactone acts as a quorum sensing signal molecule, enabling bacteria to coordinate the production of carbapenem antibiotics in a cell density-dependent manner. N-(3-Oxohexanoyl)-L-homoserine lactone is used to study bacterial quorum sensing mechanisms, especially the secondary metabolism and virulence factor regulatory pathways of Erwinia carotovora and Yersinia enterocolitica .
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Cat. No.: HY-P2522
CAS No.: 1174553-84-4
Target:  

Bacterial

Research Areas:  

Infection

Competence-Stimulating Peptide-2 (CSP-2) is a 17-amino acid signal peptide produced by Streptococcus pneumoniae, with an EC50 of 50.7 nM for its compatible receptor ComD2. Competence-Stimulating Peptide-2 (CSP-2) can regulate bacterial phenotypes such as competence development, virulence, and biofilm formation through quorum sensing .
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Cat. No.: HY-P10486
CAS No.: 200010-31-7
Target:  

Bacterial

Research Areas:  

Infection

AIP-II is a cyclic peptide signaling molecule for quorum sensing, which is produced by Staphylococcus aureus. AIP-II potently inhibits AgrC-III in Methicillin (HY-121544)-resistant type III Staphylococcus aureus strain AH1747, with an IC50 of 0.532 nM. AIP-II binds to the AgrC-II receptor and regulates virulence gene expression in Staphylococcus aureus .
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Cat. No.: HY-W008270
CAS No.: 497-23-4
Synonyms: γ-Crotonolactone
2(5H)-Furanone (γ-Crotonolactone) is an endogenous metabolite. 2(5H)-Furanone mimics N-acyl homoserine lactone signals, occupies the binding site of LuxR homologs, and interferes with quorum sensing-mediated gene regulation. 2(5H)-Furanone inhibits quorum sensing mediated by AHLs with different acyl chain lengths. 2(5H)-Furanone inhibits biofilm formation of environmental Aeromonas hydrophila strains on polystyrene plates. 2(5H)-Furanone suppresses spike-and-wave discharges in a rat model of generalized absence seizures and exhibits selective activity against absence seizures. 2(5H)-Furanone can be used in studies related to bacteria infections and generalized absence seizures.
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Cat. No.: HY-W045071
CAS No.: 106983-28-2
Target:  

Bacterial

Research Areas:  

Infection

N-Hexanoyl-DL-homoserine lactone is a bacterial quorum sensing molecule produced in the rhizosphere. N-Hexanoyl-DL-homoserine lactone, a bacterial quorum sensing signal, induces transcriptional changes in Arabidopsis and may contribute to tuning plant growth to the microbial composition of the rhizosphere .
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Cat. No.: HY-108700
CAS No.: 147795-39-9
Purity:  98.05%
Target:  

SOD

Research Areas:  

Infection

N-3-Oxo-octanoyl-L-homoserine lactone, a quorum-sensing signal, is an Agrobacterium autoinducer .
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Cat. No.: HY-W342499
CAS No.: 55682-83-2
Synonyms: Methyl 3-hydroxytetradecanoate; 3-OH PAME; Methyl 3-hydroxymyristate
Target:  

Fungal

Research Areas:  

Metabolic Disease

3-Hydroxy myristic acid methyl ester (Methyl 3-hydroxytetradecanoate) is the quorum-sensing signal molecule (quormone), which regulates the virulence of Ralstonia solanacearum .
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Cat. No.: HY-W035904
CAS No.: 539-80-0
Synonyms: Cycloheptatrienone
Tropone (Cycloheptatrienone) is a non-benzenoid aromatic natural product that acts as a membrane reverse transporter and metal chelator. Tropone disrupts the proton motive force by affecting the transmembrane proton gradient and functions as a quorum sensing signal through LuxR-type transcriptional regulators. Tropone exhibits broad-spectrum antibiotic, anticancer, algicidal, and probiotic activities. As a virulence factor toxic to rice seedlings, Tropone promotes biofilm formation in Burkholderia plantarii and induces neurotoxicity involving mitochondrial and cytoskeletal damage, increased Ca 2+ influx, and oxidative stress. Tropone is used in the study of bacterial infections .
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Cat. No.: HY-133683
CAS No.: 503610-29-5
Purity:  95.20%
Synonyms: 3-Oxo-C14-AHL
N-(3-Oxotetradecanoyl)-DL-homoserine lactone, a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, is a quorum sensing (QS) signaling molecule .
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Cat. No.: HY-W015800
CAS No.: 2185-03-7
Target:  

Drug Intermediate

Research Areas:  

Others

L-Homoserine lactone hydrochloride is the core structural unit of the bacterial quorum-sensing signal molecule N-acyl-L-homoserine lactone (AHLs). As an important intermediate, L-Homoserine lactone hydrochloride acylated derivatives have potent immunosuppressive activity .
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Cat. No.: HY-126858
CAS No.: 340774-69-8
Purity:  98.00%
Synonyms: (+)-Ambuic acid
Ambuic acid exhibits antimicrobial activity against Staphylococcus aureus, with IC50 of 43.9 μM for strain ATCC 6538. Ambuic acid is an inhbitor for the biosynthesis of cyclic peptide quorum sensing molecules (quormones) in gram-positive bacteria. Ambuic acid exhibits anti-inflammatory activity through ERK/JNK/MAPK signaling pathway .
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Cat. No.: HY-134215
CAS No.: 677354-23-3
Target:  

Bacterial Fungal

Research Areas:  

Infection

cis-11-Methyl-2-dodecenoic acid is a quorum sensing (QS) signal that acts as a diffusion signaling factor (DSF) in extracellular microbial and fungal communication systems. DSF is involved in the regulation of virulence and biofilm formation of a variety of bacterial pathogens .
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