1 Result for "

reaction hijacking

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "reaction hijacking" in MCE Product Catalog:

Cat. No.: HY-162238
CAS No.: 2650846-59-4
Target:  

Parasite

Research Areas:  

Infection

OSM-S-106 is a species-selective reaction hijacking pro-inhibitor targeting the cytosolic asparaginyl-tRNA synthetase (PfAsnRS) of Plasmodium falciparum. OSM-S-106 undergoes PfAsnRS-mediated reaction hijacking to form the Asn-OSM-S-106 adduct, which blocks the PfAsnRS catalytic cycle, inhibits protein translation, and activates the amino acid starvation response. OSM-S-106 is useful for research on malaria, PfAsnRS, and the reaction hijacking mechanism of aminoacyl-tRNA synthetases .
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