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ruthenium

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42

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4

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4

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4

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2

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3

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1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-103311
    Ruthenium red
    Maximum Cited Publications
    15 Publications Verification

    Ammoniated ruthenium oxychloride

    		 Calcium Channel Cardiovascular Disease
    Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids and binds to acidic mucopolysaccharides. Ruthenium red is a L-type calcium current (ICa) blocker .
    Ruthenium red
  • HY-W074143
    Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride
    5+ Cited Publications

    		 Fluorescent Dye Others
    Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride ([Ru(dpp)3] 2+) is an electrochemiluminescent (ECL) probe and oxygen-sensitive sensor. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride can be used to modify electrode surfaces for the detection of sulfates (S2O8 2-) and oxalates, based on electrochemical reactions that generate excited-state species, releasing photons through irreversible redox reactions. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride utilizes the oxygen quenching of fluorescence mechanism, where fluorescence intensity reflects the metabolic rate of living microorganisms or oxygen levels within cells/tumors, allowing for real-time detection. Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride's main applications include microbial detection, antibacterial activity studies, and tumor microenvironment research .
    Tris(4,7-diphenyl-1,10-phenanthroline)ruthenium(II) dichloride
  • HY-16350
    BOLD-100
    1 Publications Verification

    NKP-1339; IT-139; KP-1339

    		 DNA/RNA Synthesis Apoptosis Cancer
    BOLD-100 (NKP-1339; IT-139) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. BOLD-100 induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. BOLD-100 has a high tumor targeting potential, strongly binds to serum proteins such as albumin and transferrin and activates in the reductive tumor milieu .
    BOLD-100
  • HY-59137
    1-Methylimidazole

    		Drug Intermediate Cancer
    1-Methylimidazole acts as a membrane performance regulator that promotes the formation of reverse osmosis membranes with a dense ultra-thin polyamide layer. Such membranes exhibit higher flux and salt rejection rate, while also conferring excellent pH stability to the membrane. 1-Methylimidazole can serve as a ligand for ruthenium (II) complexes to construct metal-based anticancer agents .
    1-Methylimidazole
  • HY-W127716
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2
    1 Publications Verification

    		 Fluorescent Dye Cancer
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs) .
    Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2
  • HY-Y1109
    Dichloro(p-cymene)ruthenium(II) dimer

    Tetrachlorobis(mu-4-cymene)diruthenium(II)

    		 Biochemical Assay Reagents Cancer
    Dichloro(p-cymene)ruthenium(II) dimer (Tetrachlorobis(mu-4-cymene)diruthenium(II)) is a ruthenium-based organometallic catalyst precursor, which is widely applied in the field of organic synthesis .
    Dichloro(p-cymene)ruthenium(II) dimer
  • HY-19376
    NAMI-A

    		FAK Cancer
    NAMI-A is a ruthenium-based drug characterised by the selective activity against tumour metastases, inhibits the adhesion and migration.
    NAMI-A
  • HY-W127790
    Bathophenanthrolinedisulfonic acid disodium

    		Biochemical Assay Reagents Others
    Bathophenanthrolinedisulfonic acid disodium salt (BPS) is a colorimetric reagent for iron detection, with a wavelength of 535 nm for iron complex. It can be used for iron determination in aqueous solution systems without the need for extraction solvents. BPS can serve as a precursor to prepare Europium(III) tris(dibenzoylmethanate) bis(bathophenanthrolinedisulfonate) complex and ruthenium(II) tris(bathophenanthrolinedisulfonate), or participate in the catalytic oxidation of 2-hexanol by forming water-soluble complexes with palladium .
    Bathophenanthrolinedisulfonic acid disodium
  • HY-W033466
    Dichloro(benzene)ruthenium(II) dimer

    Benzeneruthenium(II) chloride dimer

    		 Biochemical Assay Reagents Others
    Benzeneruthenium(II) Chloride Dimer (Benzeneruthenium(II) chloride dimer) is a dinuclear complex. Benzeneruthenium(II) Chloride Dimer undergoes a hydrolysis reaction to generate a mixture of mononuclear ruthenium complexes in equilibrium .
    Dichloro(benzene)ruthenium(II) dimer
  • HY-W020958
    Ru(acac)3

    Tris(acetylacetonato)ruthenium (III)

    		 Caspase Apoptosis Cancer
    Ru (acac) 3 (Tris (acetylacetonato) ruthenium (III)) is a caspase-3 activator and Apoptosis inducer. Ru (acac) 3 exerts growth inhibitory effects on various cell lines in vitro by inhibiting DNA/RNA synthesis and inducing mild reversible S-phase cell cycle arrest. Ru (acac) 3 is commonly used in research related to ovarian cancer, osteosarcoma, cervical cancer, melanoma, and other fields .
    Ru(acac)3
  • HY-79986
    Diiodo(p-cymene)ruthenium(II) dimer

    		Drug Intermediate Others
    Diiodo(p-cymene)ruthenium(II) dimer is a drug intermediate for synthesis of various active compounds.
    Diiodo(p-cymene)ruthenium(II) dimer
  • HY-W127832
    Ru(dpp)3(PF6)2
    1 Publications Verification

    		 Fluorescent Dye Others
    Ru(dpp)3(PF6)2 is a complex containing metallic ruthenium (Ru) and is a chemiluminescent oxygen probe. [Ru(dpp)3] 2+ is a luminescent substance that can undergo metal-to-ligand charge transfer (MLCT), and fluorescence will appear during the transfer of Ru to the ligand. At the same time, the fluorescence of Ru(dpp)3(PF6)2 is effectively quenched by molecular oxygen, so it is widely used in biosensors, environmental monitoring, and materials science. The property of Ru(dpp)3(PF6)2, which oxidizes Ru 2+ to Ru 3+, has also been used to design and construct solid-state light-emitting electrochemical cells .
    Ru(dpp)3(PF6)2
  • HY-D1708
    RuBP-4S

    		Fluorescent Dye Others
    RuBP-4S is a luminescent ruthenium complex.
    RuBP-4S
  • HY-W140535
    Tetrasodium,4-(1,10-phenanthrolin-4-yl)benzenesulfonate,ruthenium((II))

    		Fluorescent Dye MOFs Others
    Tetrasodium, 4-(1,10-phenanthrolin-4-yl)benzenesulfonate,ruthenium((II)) is a luminescent ruthenium complex. Tetrasodium, 4-(1,10-phenanthrolin-4-yl)benzenesulfonate,ruthenium((II)) is used in biological and chemical fields as a fluorescent indicator dye and an electrochemiluminescent probe .
    Tetrasodium,4-(1,10-phenanthrolin-4-yl)benzenesulfonate,ruthenium((II))
  • HY-147039
    BOLD-100 free base

    NKP-1339 free base; IT-139 free base; KP-1339 free base

    		 HSP Autophagy Cancer
    BOLD-100 (NKP-1339; IT-139) free base is a ruthenium-based anticancer agent. BOLD-100 free base also is an inhibitor of stress-induced GRP78 upregulation, disrupting endoplasmic reticulum (ER) homeostasis and inducing ER stress and unfolded protein response (UPR). BOLD-100 free base interferes with the complex interplay between ER-stress response, lysosome dynamics, and autophagy execution .
    BOLD-100 free base
  • HY-Y1312
    2-Phenylimidazole

    PhI; 2PZ

    		 Biochemical Assay Reagents Others
    2-Phenylimidazole (PhI) is a corrosion inhibitor for brass and can be used to prepare complexes with ruthenium (III) .
    2-Phenylimidazole
  • HY-P4599
    H-His-His-OH

    		Biochemical Assay Reagents Others
    H-His-His-OH is an oligopeptide. H-His-His-OH can chelate with Ruthenium (II). H-His-His-OH inhibits the hydrolysis of metal ions at pH 7.4 .
    H-His-His-OH
  • HY-W110791
    Sodium diphenylamine-4-sulfonate

    		Biochemical Assay Reagents Others
    Sodium diphenylamine-4-sulfonate is a chemical indicator commonly used in redox titrations. Its reduced state is colorless and its oxidized state is reddish-purple. Sodium diphenylamine-4-sulfonate is also a quencher and reducing agent. Sodium diphenylamine-4-sulfonate inhibits the electrochemiluminescence of the ruthenium tris(bipyridine) system through energy transfer. Sodium diphenylamine-4-sulfonate participates in the synthesis of nanocrystals .
    Sodium diphenylamine-4-sulfonate
  • HY-59137S
    1-Methylimidazole-d6

    		Isotope-Labeled Compounds Drug Intermediate Cancer
    1-Methylimidazole-d6 is the deuterium labeled 1-Methylimidazole. 1-Methylimidazole acts as a membrane performance regulator that promotes the formation of reverse osmosis membranes with a dense ultra-thin polyamide layer. Such membranes exhibit higher flux and salt rejection rate, while also conferring excellent pH stability to the membrane. 1-Methylimidazole can serve as a ligand for ruthenium (II) complexes to construct metal-based anticancer agents.
    1-Methylimidazole-d6
  • HY-156786
    TLD-1433

    		Reactive Oxygen Species (ROS) Influenza Virus SARS-CoV HSV Infection
    TLD-1433 is the fourth-generation ruthenium (II) based photodynamic compound (PDC). TLD-1433 is activated by green light (525 ± 25 nm) and efficiently generates ROS to achieve pathogen inactivation. After photoinactivation, TLD-1433 significantly induces lipid peroxidation of the cell membrane, which can directly damage the integrity of the viral envelope. TLD-1433 has ID50 for enveloped viruses (such as H1N1 influenza virus, coronavirus OC43, HSV-1, Zika virus) is as low as nanomolar level; for non-enveloped viruses (such as adenovirus Ad5, mammalian rotavirus MRV), a concentration of micro-molar level is required for inactivation. TLD-1433 has antigen retention property and can be used for the preparation of inactivated vaccines .
    TLD-1433
  • HY-34544
    2-Hexylthiophene

    		Others Others
    2-Hexylthiophene is an extremely weak basic heteroaromatic compound. 2-Hexylthiophene can be used to modify and improve the molar absorption coefficient of ruthenium sensitizer
    2-Hexylthiophene
  • HY-W035145
    Tris2,2′-bipyridineruthenium(II) hexafluorophosphate

    		Drug Intermediate Others
    Tris(2,2′-bipyridine)ruthenium(II)hexafluorophosphate can be used to prepare Ru(II)-containing photodynamic therapy (PDT) photosensitizers .
    Tris2,2′-bipyridineruthenium(II) hexafluorophosphate
  • HY-103527
    RuBi-GABA

    		GABA Receptor Neurological Disease
    RuBi-GABA is a new ruthenium-based caged GABA compound. RuBi-GABA photocleaves and releases GABA after being excited with visible wavelengths. RuBi-GABA produces gaba receptor-mediated currents .
    RuBi-GABA
  • HY-126060
    9-Ethylguanine

    		Nucleoside Antimetabolite/Analog Cancer
    9-Ethylguanine is a modified nucleobase derived from guanine that coordinates to azolato-bridged dinuclear platinum(II) complexes via its N7 nitrogen atom. 9-Ethylguanine forms adducts with a ruthenium(II) complex via the N7 position of its guanine moiety .
    9-Ethylguanine
  • HY-W034154
    Dihydridotetrakis(triphenylphosphine)ruthenium(II)

    Tetrakis(triphenylphosphine)ruthenium dihydride

    		 Drug Intermediate Endogenous Metabolite
    Dihydridotetrakis(triphenylphosphine)ruthenium(II) (Tetrakis(triphenylphosphine)ruthenium dihydride) is a catalyst with good catalytic activity. Dihydridotetrakis(triphenylphosphine)ruthenium(II) can be used in organic synthesis reactions, especially in hydrogenation and dehydrogenation reactions. Dihydridotetrakis(triphenylphosphine)ruthenium(II) has received extensive attention in the study of metal catalysts, and its high efficiency makes it an ideal research object.
    Dihydridotetrakis(triphenylphosphine)ruthenium(II)
  • HY-W591060
    Bisbipyridine-(5-aminophenanthroline)

    		Biochemical Assay Reagents Endogenous Metabolite
    Bis(bipyridine)-(5-aminophenanthroline) is an organic catalyst with photocatalytic activity. The use of Bis(bipyridine)-(5-aminophenanthroline) in hematology involves its use as a stain for tissue diagnosis. Bis(bipyridine)-(5-aminophenanthroline) can be used as a transition metal catalyst in catalytic reactions. Bis(bipyridine)-(5-aminophenanthroline) has also been used in the study of ruthenium catalysts.
    Bisbipyridine-(5-aminophenanthroline)
  • HY-150966
    Antiproliferative agent-10

    		Mitochondrial Metabolism Cancer
    Antiproliferative agent-10 (compound 8) is an anti-tumour ruthenium(II)-tris-pyrazolylmethane complex that inhibits the growth of cancer cells by inhibiting mitochondrial calcium uptake .
    Antiproliferative agent-10
  • HY-150969
    Antiproliferative agent-12

    		Mitochondrial Metabolism Cancer
    Antiproliferative agent-10 (compound 1) is an anti-tumour ruthenium(II)-tris-pyrazolylmethane complex that inhibits the growth of cancer cells by inhibiting mitochondrial calcium uptake .
    Antiproliferative agent-12
  • HY-162569
    Ru-TRZ2

    		Apoptosis Necroptosis Cancer
    Ru-TRZ2 is a potent ruthenium-based chemotherapeutic agent. Ru-TRZ2 induces apoptosis and necroptosis. Ru-TRZ2 shows antitumor activity .
    Ru-TRZ2
  • HY-157051
    [Ru(DIP)2TAP]Cl2

    		Photosensitizer Cancer
    [Ru(DIP)2TAP]Cl2, Ruthenium(II) polypyridyl compound, is a photosensitizer. [Ru(DIP)2TAP]Cl2 can be used for the research of photodynamic therapy (PDT) .
    [Ru(DIP)2TAP]Cl2
  • HY-150968
    Antiproliferative agent-11

    		Apoptosis Cancer
    Antiproliferative agent-11 (compound 7) is an antiproliferative and selective Ruthenium(II)-Tris-pyrazolylmethane complex. Antiproliferative agent-11 shows antiproliferative activity towards MCF-7, HeLa, 518A2, HCT116 and RD with IC50s of 6, 10, 6.8, 6.7 and 6 μM, respectively. Antiproliferative agent-11 can be used for the research of cancer .
    Antiproliferative agent-11
  • HY-59137S1
    1-Methyl-imidazole-d3

    		Isotope-Labeled Compounds Drug Intermediate Cancer
    1-Methylimidazole-d3 is the deuterium labeled 1-Methylimidazole. 1-Methylimidazole acts as a membrane performance regulator that promotes the formation of reverse osmosis membranes with a dense ultra-thin polyamide layer. Such membranes exhibit higher flux and salt rejection rate, while also conferring excellent pH stability to the membrane. 1-Methylimidazole can serve as a ligand for ruthenium (II) complexes to construct metal-based anticancer agents.
    1-Methyl-imidazole-d3
  • HY-59137S2
    1-Methylimidazole-d3-1

    		Isotope-Labeled Compounds Drug Intermediate Cancer
    1-Methylimidazole-d3-1 is the deuterium labeled 1-Methylimidazole. 1-Methylimidazole acts as a membrane performance regulator that promotes the formation of reverse osmosis membranes with a dense ultra-thin polyamide layer. Such membranes exhibit higher flux and salt rejection rate, while also conferring excellent pH stability to the membrane. 1-Methylimidazole can serve as a ligand for ruthenium (II) complexes to construct metal-based anticancer agents.
    1-Methylimidazole-d3-1
  • HY-P10667
    Ac-MRGDH-NH2

    		Integrin Cancer
    Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. Ac-MRGDH-NH2 can be used to synthesize the diastereoisomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic bis-aqua ruthenium warhead [Ru(Ph2phen)2(OH2)2]2+, and Ac-MRGDH-NH2 possesses integrin targeting ability and photosubstitution properties. Therefore, Ac-MRGDH-NH2 can be utilized in research on tumor-targeted photodynamic activation chemotherapy (PACT) .
    Ac-MRGDH-NH2
  • HY-W998790
    Ruthenium(II)Phosphoramidite complex

    		DNA/RNA Synthesis Phosphoramidites Others
    Ruthenium(II)Phosphoramidite complex is a phosphoramidite that can be used in the synthesis of oligonucleotides.
    Ruthenium(II)Phosphoramidite complex
  • HY-W033559
    Carbonylhydrido(tetrahydroborato)[bis(2-diphenylphosphinoethyl) aMino]ruthenium(II)

    		Biochemical Assay Reagents Others
    Carbonylhydrido(tetrahydroborato)[bis(2-diphenylphosphinoethyl) aMino]ruthenium(II) is a ruthenium catalyst for homogeneous hydrogenations of esters under base free conditions. .
    Carbonylhydrido(tetrahydroborato)[bis(2-diphenylphosphinoethyl) aMino]ruthenium(II)
  • HY-W075614
    Tris(4,4''-dicarboxylicacid-2,2''-bipyridyl)rutheniuM(II) dichloride

    		MOFs Others
    Tris(4,4''-dicarboxylicacid-2,2''-bipyridyl)rutheniuM(II) dichloride is a metal-organic framework (MOF).
    Tris(4,4''-dicarboxylicacid-2,2''-bipyridyl)rutheniuM(II) dichloride
  • HY-W856287
    Bis(2,2'-bipyridyl)(4,4'-dicarboxyl-2,2'-bipyridyl)ruthenium(II) bishexafluorophosphate

    		MOFs Others
    Bis(2,2'-bipyridyl)(4,4'-dicarboxyl-2,2'-bipyridyl)ruthenium(II) (bishexafluorophosphate) is a metal-organic framework (MOF).
    Bis(2,2'-bipyridyl)(4,4'-dicarboxyl-2,2'-bipyridyl)ruthenium(II) bishexafluorophosphate
  • HY-W543741
    Ruthenium(2+),bis2,2'-bipyridine-κN1,κN1'4-ethenyl-4'-methyl-2,2'-bipyridine-κN1,κN1'-,(OC-6-33)-,hexafluorophosphate(1-)(1:2)

    		MOFs Others
    Ruthenium(2+),bis(2,2'-bipyridine-κN1,κN1')(4-ethenyl-4'-methyl-2,2'-bipyridine-κN1,κN1')-,(OC-6-33)-,hexafluorophosphate(1-)(1:2) is a metal-organic framework (MOF).
    Ruthenium(2+),bis2,2'-bipyridine-κN1,κN1'4-ethenyl-4'-methyl-2,2'-bipyridine-κN1,κN1'-,(OC-6-33)-,hexafluorophosphate(1-)(1:2)
  • HY-176859
    [Ru(dpp)(bpy)(mtmp)](PF6)2

    		Apoptosis Cancer
    [Ru(dpp)(bpy)(mtmp)](PF6)2 (Compound 5) is a trisheteroleptic ruthenium complex. [Ru(dpp)(bpy)(mtmp)](PF6)2 has a light-activated anticancer activity. [Ru(dpp)(bpy)(mtmp)](PF6)2 can selectively cleave off upon green light irradiation, thereby releasing a phototoxic ruthenium-based photoproduct that binds to nuclear DNA, induces DNA damage and apoptosis in cancer cells. [Ru(dpp)(bpy)(mtmp)](PF6)2 can be used for phototherapy of cancers like conjunctival melanoma research .
    [Ru(dpp)(bpy)(mtmp)](PF6)2
  • HY-P4599B
    H-His-His-OH acetate

    		Biochemical Assay Reagents Others
    H-His-His-OH acetate is an oligopeptide. H-His-His-OH acetate can chelate with Ruthenium (II). H-His-His-OH inhibits the hydrolysis of metal ions at pH 7.4 .
    H-His-His-OH acetate
  • HY-34544R
    2-Hexylthiophene (Standard)

    		Reference Standards Others Others
    Daucosterol (Standard) is the analytical standard of Daucosterol. This product is intended for research and analytical applications. Daucosterol is an orally active natural sterol compound, which has anti-inflammatory, anticancer and immunomodulatory activities. Daucosterol inhibits cancer cell proliferation by inducing autophagy through ROS-dependent manner. Daucosterol also inhibits colon cancer growth by inducing apoptosis, inhibiting cell migration and invasion and targeting caspase signalling pathway .
    2-Hexylthiophene (Standard)

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