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  3. Drug Intermediate
  4. 1-Methylimidazole

1-Methylimidazole acts as a membrane performance regulator that promotes the formation of reverse osmosis membranes with a dense ultra-thin polyamide layer. Such membranes exhibit higher flux and salt rejection rate, while also conferring excellent pH stability to the membrane. 1-Methylimidazole can serve as a ligand for ruthenium (II) complexes to construct metal-based anticancer agents.

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1-Methylimidazole

1-Methylimidazole Chemical Structure

CAS No. : 616-47-7

Size Price Stock Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO In-stock
Liquid
100 g In-stock
500 g In-stock
1 kg In-stock

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Based on 1 publication(s) in Google Scholar

Other Forms of 1-Methylimidazole:

1-Methylimidazole Related Antibodies

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Description

1-Methylimidazole acts as a membrane performance regulator that promotes the formation of reverse osmosis membranes with a dense ultra-thin polyamide layer. Such membranes exhibit higher flux and salt rejection rate, while also conferring excellent pH stability to the membrane. 1-Methylimidazole can serve as a ligand for ruthenium (II) complexes to construct metal-based anticancer agents[1][2].

In Vitro

When 1-methylimidazole (0.3% w/v) is introduced into the aqueous phase during the interfacial polymerization process, a reverse osmosis membrane can be prepared. Compared with the control membrane, this membrane has a thinner and denser polyamide layer, more backside pores, larger pore size, and smaller free volume[1].
Free 1-methylimidazole acts as a metal ligand for the synthesis of ruthenium (II) complexes with anticancer activity[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1-Methylimidazole Related Antibodies
Molecular Weight

82.10

Formula

C4H6N2
CAS No.
Appearance

Liquid (Density: 1.035 g/cm3)

Color

Colorless to light yellow

SMILES

CN1C=CN=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (2436.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 12.1803 mL 60.9013 mL 121.8027 mL
5 mM 2.4361 mL 12.1803 mL 24.3605 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.99%

SDS (642 KB)

COA (250 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 12.1803 mL 60.9013 mL 121.8027 mL 304.5067 mL
5 mM 2.4361 mL 12.1803 mL 24.3605 mL 60.9013 mL
10 mM 1.2180 mL 6.0901 mL 12.1803 mL 30.4507 mL
15 mM 0.8120 mL 4.0601 mL 8.1202 mL 20.3004 mL
20 mM 0.6090 mL 3.0451 mL 6.0901 mL 15.2253 mL
25 mM 0.4872 mL 2.4361 mL 4.8721 mL 12.1803 mL
30 mM 0.4060 mL 2.0300 mL 4.0601 mL 10.1502 mL
40 mM 0.3045 mL 1.5225 mL 3.0451 mL 7.6127 mL
50 mM 0.2436 mL 1.2180 mL 2.4361 mL 6.0901 mL
60 mM 0.2030 mL 1.0150 mL 2.0300 mL 5.0751 mL
80 mM 0.1523 mL 0.7613 mL 1.5225 mL 3.8063 mL
100 mM 0.1218 mL 0.6090 mL 1.2180 mL 3.0451 mL
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1-Methylimidazole Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Methylimidazole616-47-7Drug IntermediateDrug IintermediateXPSNaClpolyamide layerimidazolium salttrimesoyl chloridenon-small cell lung cancer cellshuman non-small cell lung cancer A549 cellsFTIRcarboxylic acid groupsreverse osmosis membraneInhibitorinhibitorinhibit

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