BOLD-100 free base

(Synonyms: NKP-1339 free base; IT-139 free base; KP-1339 free base)
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BOLD-100 (NKP-1339; IT-139) free base is a ruthenium-based anticancer agent. BOLD-100 free base also is an inhibitor of stress-induced GRP78 upregulation, disrupting endoplasmic reticulum (ER) homeostasis and inducing ER stress and unfolded protein response (UPR). BOLD-100 free base interferes with the complex interplay between ER-stress response, lysosome dynamics, and autophagy execution.

For research use only. We do not sell to patients.

  • CAS No.: 783324-98-1
  • Formula: C14H12Cl4N4Ru
  • Molecular Weight:479.15
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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