H-His-His-OH
H-His-His-OH is a dipeptide containing two histidine residues and can serve as a model ligand for histidine-containing oligopeptides. H-His-His-OH forms [MLH]2+ complexes with Ru (II) precursors under acidic conditions and inhibits metal ion hydrolysis at physiological pH. H-His-His-OH can be used in metal coordination chemistry and cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 306-14-9
- Formula: C12H16N6O3
- Molecular Weight:292.29
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MDCK | EC50 |
0.37 mM
Compound: 42
|
Activation of human PEPT1 expressed in MDCK cells
Activation of human PEPT1 expressed in MDCK cells
|
[PMID: 16759105] |
| MDCK | IC50 |
0.4 mM
Compound: 42
|
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
|
[PMID: 16759105] |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 306-14-9
-
Molecular Weight 292.29
-
Formula C12H16N6O3
-
Sequence
His-His
-
Sequence Shortening
HH
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)