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site IQ electron leak

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Cat. No.: HY-129115
CAS No.: 897613-29-5
Research Areas:  

Inflammation/Immunology

S1QEL1.1 is a cell-permeable selective site IQ electron leak inhibitor and mitochondrial complex I site IQ superoxide/hydrogen peroxide production inhibitor (IC50 of 70.3 nM for IQr; IC50 of 64.0 nM for IQf), exerting cytoprotective effects by inhibiting site IQ-dependent ROS production during reverse and forward electron transport without affecting oxidative phosphorylation and normal electron transport. S1QEL1.1 can be used for research on ischemia-reperfusion injury .
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