21 Results for "

somatostatin release

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "somatostatin release" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-103277A
Purity:  96.20%
Target:  

Bombesin Receptor

BIM 23042 TFA, a certain somatostatin (SS) octapeptide analogue, is a selective neuropeptide neuromedin B receptor (NMB-R, BB1) antagonist. BIM 23042 has 100-fold lower affinity for gastrin-releasing peptide (GRP) receptor (BB2). BIM 23042 inhibits Neuromedin?B?(HY-P0241), ICI 216140 and DPDM-bombesin ethylamide-induced Ca 2+ release .
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Cat. No.: HY-P0084
CAS No.: 38916-34-6
Synonyms: SRIF-14; somatostatin-14
Cyclic somatostatin (SRIF-14) is a growth hormone-release inhibiting factor used in the research of severe, acute hemorrhages of gastroduodenal ulcers. Cyclic somatostatin is a neuropeptide co-stored with acetylcholine in the cardiac parasympathetic innervation, exerts influences directly on contraction of ventricular cardiomyocytes. Cyclic somatostatin inhibits the contractile response of isoprenaline with an IC50 value of 13 nM. Cyclic somatostatin can be used for the research of cardiovascular disease .
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Cat. No.: HY-P1782
CAS No.: 155069-90-2
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Calcitonin (8-32), salmon is a highly selective Amylin receptor antagonist. Calcitonin (8-32), salmon reverses the Amylin-mediated inhibition of glucose-induced insulin release, but has no effect on either glucagon release or somatostatin release. Calcitonin (8-32), salmon can be used for studies related to β-cell amylin .
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Cat. No.: HY-P3579
CAS No.: 11063-17-5
Synonyms: GIP (1-42), porcine
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Gastric Inhibitory Peptide (GIP (1-42)), porcine is a porcine glucose-dependent insulinotropic polypeptide and inhibitor of pentagastrin-stimulated gastric acid secretion. Gastric Inhibitory Peptide, porcine stimulates endogenous somatostatin release. Gastric Inhibitory Peptide, porcine acts in a dose- and time-dependent manner in conscious, chronic gastric fistula-equipped rats .
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Cat. No.: HY-P0039
CAS No.: 136207-23-3
Target:  

Bombesin Receptor

Research Areas:  

Cancer

BIM-26226 is a selective gastrin-releasing peptide receptor (GRPR) (IC50 = 6 nM) and bombesin receptor (BN receptor) antagonist. BIM-26226 antagonizes BN- or GRP-stimulated amylase release with IC50 values of 0.3 nM and 0.2 nM, respectively. BIM-26226 is specific for the GRP-preferring BN receptor subtype with no interference with GRP receptor system. BIM-26226 can induce the synthesis of somatostatin receptor but has no significant effect on tumor growth .
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Cat. No.: HY-P3019
CAS No.: 357952-09-1
Urocortin III (human) is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III (human) preferentially binds and activates CRF-R2 and has a discrete central nervous system and peripheral distribution. Urocortin III (human) potently binds to type 2 CRF receptors, specifically mCRF (Ki = 13.5 nM) and rCRF (Ki = 21.7 nM), while demonstrating negligible affinity for hCRF1 (Ki >100 nM). Urocortin III (human) mediates somatostatin-dependent negative feedback control of Insulin (human) (HY-P0035) secretion [1][2].
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Cat. No.: HY-133025
CAS No.: 283167-06-6
Purity:  99.89%
Target:  

Somatostatin Receptor

Research Areas:  

Neurological Disease

FK962 is an enhancer of somatostatin release, exerts cognitive-enhancing actions. Anti-dementia properties .
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Cat. No.: HY-103277
CAS No.: 111857-96-6
Target:  

Bombesin Receptor

BIM 23042, a certain somatostatin (SS) octapeptide analogue, is a selective neuropeptide neuromedin B receptor (NMB-R, BB1) antagonist. BIM 23042 has 100-fold lower affinity for gastrin-releasing peptide (GRP) receptor (BB2). BIM 23042 inhibits Neuromedin?B?(HY-P0241), ICI 216140 and DPDM-bombesin ethylamide-induced Ca 2+ release .
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Cat. No.: HY-P3019A
Urocortin III (human) TFA is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III (human) TFA preferentially binds and activates CRF-R2 and has a discrete central nervous system and peripheral distribution. Urocortin III (human) TFA potently binds to type 2 CRF receptors, specifically mCRF (Ki = 13.5 nM) and rCRF (Ki = 21.7 nM), while demonstrating negligible affinity for hCRF1 (Ki >100 nM). Urocortin III (human) TFA mediates somatostatin-dependent negative feedback control of Insulin (human) (HY-P0035) secretion .
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Cat. No.: HY-P3899A
Target:  

Somatostatin Receptor

Research Areas:  

Metabolic Disease

[Nle8] Somatostatin (1-28) TFA is a derivative of somatosttin (1-28) with norleucine replacing methionine in position 8. [Nle8] Somatostatin (1-28) TFA increases the amylase release.[Nle8] Somatostatin (1-28) TFA increases the cyclic AMP in pancreatic acini .
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Cat. No.: HY-P2090A
CAS No.: 2478421-60-0
Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, is a weak sst2/sst5 receptor partial agonist with IC50 values of 0.26 nM and 6.92 nM, respectively. Angiopeptin TFA is a potent inhibitor of growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin TFA inhibits adenylate cyclase or stimulates extracellular acidification. Angiopeptin TFA has the potential for coronary atherosclerosis research .
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Cat. No.: HY-P0084A
CAS No.: 54472-66-1
Synonyms: SRIF-14 acetate; somatostatin-14 acetate
Cyclic somatostatin (SRIF-14) acetate is a growth hormone-release inhibiting factor used in the research of severe, acute hemorrhages of gastroduodenal ulcers. Cyclic somatostatin acetate is a neuropeptide co-stored with acetylcholine in the cardiac parasympathetic innervation, exerts influences directly on contraction of ventricular cardiomyocytes. Cyclic somatostatin acetate inhibits the contractile response of isoprenaline with an IC50 value of 13 nM. Cyclic somatostatin acetate can be used for the research of cardiovascular disease .
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Cat. No.: HY-120287
CAS No.: 214348-67-1
Target:  

Somatostatin Receptor

Research Areas:  

Endocrinology

L-054522 is an agonist for somatostatin receptor subtype 2 with Kd of 0.01 nM. L-054522 inhibits growth hormone release from rat primary pituitary cell (IC50=0.05 nM) and glucagon and insulin release from isolated mouse pancreatic islet cell (IC50=0.05 nM and 12 nM) .
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Cat. No.: HY-P3958
CAS No.: 78981-49-4
BIM-23027 is a selective agonist of sst2 receptor (EC50=0.32 nM), with similar effect to somatostatin (SRIF), a cyclic tetradecapeptide. BIM-23027 stimulates dopamine release, which is mediated by a Glu-dependent mechanism .
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Cat. No.: HY-P2229
CAS No.: 119719-11-8
Synonyms: SDZ CO 611
Target:  

Somatostatin Receptor

Research Areas:  

Cancer

Ilatreotide (SDZ CO61), glycated somatostatin derivative, is a highly potent glycated analog of somatostatin with improved oral activity. Ilatreotide can suppress the fasting level and postprandial release of several gastrointestinal and pancreatic hormones. Ilatreotide can be used for the research of gastroenteropancreatic tumors .
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Cat. No.: HY-P3899
CAS No.: 84768-30-9
Target:  

Somatostatin Receptor

Research Areas:  

Metabolic Disease

[Nle8] Somatostatin (1-28) is a derivative of somatosttin (1-28) with norleucine replacing methionine in position 8. [Nle8] Somatostatin (1-28) increases the amylase release.[Nle8] Somatostatin (1-28) increases the cyclic AMP in pancreatic acini .
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Cat. No.: HY-P3578
CAS No.: 134875-67-5
Target:  

Insulin Receptor

Research Areas:  

Endocrinology

Gastric Inhibitory Polypeptide (1-30), porcine lacks the C-terminal 12 amino acid residues of natural gastric inhibitory polypeptide (GIP), exhibits biologic activity by potentiating the release of insulin and somatostatin .
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Cat. No.: HY-P0221B
Target:  

PACAP Receptor

Research Areas:  

Endocrinology

PACAP (1-38) free acid TFA is an endogenous neuropeptide. PACAP (1-38) free acid TFA potently stimulates antral motility and somatostatin secretion, inhibits the secretion of gastrin and stimulates the release of vasoactive intestinal polypeptide, gastrin releasing peptide and substance P. PACAP (1-38) free acid TFA also enhances N-methyl-D-aspartate receptor function and expression of brain-derived neurotrophic factor through RACK1 .
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Cat. No.: HY-P2090
CAS No.: 113294-82-9
Angiopeptin, a cyclic octapeptide analogue of somatostatin, is a weak sst2/sst5 receptor partial agonist with IC50 values of 0.26 nM and 6.92 nM, respectively. Angiopeptin is a potent inhibitor of growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin inhibits adenylate cyclase or stimulates extracellular acidification. Angiopeptin has the potential for coronary atherosclerosis research .
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Cat. No.: HY-P2167
CAS No.: 99685-66-2
Somatostatin RC-102 is an octapeptide analog of Somatostatin. Somatostatin RC-102 inhibits the release of growth hormone and insulin. Somatostatin RC-102 enhances the inhibition of cell migration by increasing the production or activity of LMIF, but exerts no effect on cell migration in the absence of exposure to cardiac antigens or phytohemagglutinin. Somatostatin RC-102 inhibits gastric acid secretion. Somatostatin RC-102 can be used in the research of heart diseases .
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