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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
tetrahydrobiopterin
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "tetrahydrobiopterin" in MCE Product Catalog:
Synonyms: (Rac)-Sapropterin
Category:
Alkaloids Other Alkaloids Disease markers Endogenous metabolite Disease Research Fields Inflammation/Immunology Cardiovascular System Disorder
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2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis). 2,4-Diamino-6-hydroxypyrimidine blocks Tetrahydrobiopterin (BH4) synthesis and suppresses NO production .
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1 Cited Publications
Cat. No.: HY-W097570
CAS No.: 38006-08-5
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Sulfamonomethoxine sodium is an orally active broad-spectrum synthetic sulfonamide antibiotic that inhibits dihydropteroate synthetase. Sulfamonomethoxine sodium increases blood glucose levels, induces anxiety-related activities and impairs spatial learning and memory. Sulfamonomethoxine sodium can be used for the research of anxiety, spatial memory impairment, colisepticemia, salmonellosis, and staphylococcus infection .
Cat. No.: HY-162060
CAS No.: 2894823-79-9
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YPX-C-05 is an orally active HDAC inhibitor and vasodilator. YPX-C-05 inhibits HDAC enzymatic activity, increases histone H4 acetylation, activates the PI3K/Akt pathway, promotes Akt and eNOS phosphorylation, enhances eNOS activity, and boosts nitric oxide production. YPX-C-05 increases Tetrahydrobiopterin (HY-107383) levels, restores serum nitric oxide levels, reduces endothelin-1 levels, and improves endothelial function. YPX-C-05 reduces vascular remodeling and exerts antihypertensive effects in hypertensive Mus musculus mice. YPX-C-05 can be used for the research of hypertension .
Cat. No.: HY-170236
CAS No.: 2945955-27-9
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nNOS-IN-5 (Compound 9) is a potent human neuronal NOS (nNOS) inhibitor (Ki = 22 nM). nNOS-IN-5 exhibits excellent selectivity, with a 900-fold preference for human nNOS over human endothelial NOS (eNOS). nNOS-IN-5 can be used for neurodegenerative diseases study, such as Alzheimer's disease and Parkinson’s disease .
Cat. No.: HY-100954R
CAS No.: 56-06-4
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2,4-Diamino-6-hydroxypyrimidine (Standard) is the analytical standard of 2,4-Diamino-6-hydroxypyrimidine. This product is intended for research and analytical applications. 2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis). 2,4-Diamino-6-hydroxypyrimidine blocks Tetrahydrobiopterin (BH4) synthesis and suppresses NO production .
Cat. No.: HY-W097570R
CAS No.: 38006-08-5
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Sulfamonomethoxine sodium (Standard) is the analytical standard of Sulfamonomethoxine sodium. This product is intended for research and analytical applications. Sulfamonomethoxine sodium is an orally active broad-spectrum synthetic sulfonamide antibiotic that inhibits dihydropteroate synthetase. Sulfamonomethoxine sodium increases blood glucose levels, induces anxiety-related activities and impairs spatial learning and memory. Sulfamonomethoxine sodium can be used for the research of anxiety, spatial memory impairment, colisepticemia, salmonellosis, and staphylococcus infection .
Cat. No.: HY-187029
CAS No.: 1274711-50-0
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GCH-I-IN-1 is a GCH-I inhibitor with an undefined potency profile. GCH-I-IN-1 blocks the rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis. GCH-I-IN-1 can be used for the research of pain (inflammatory pain, nociceptive pain, functional pain, or neuropathic pain) .
Cat. No.: HY-E71803
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4a-Hydroxytetrahydrobiopterin dehydratase (EC 4.2.1.96) is a lyase that can convert (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin into (6R)-L-erythro-6,7-dihydrobiopterin and H2O.
Cat. No.: HY-117551
CAS No.: 14231-41-5
Synonyms: NSC 524120
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Tetrahydroaminopterin (NSC 524120) is a tetrahydropteridine analog and the tetrahydro-reduced derivative of aminopterin. Tetrahydroaminopterin is used for studies on phenylalanine hydroxylase cofactor binding and the structure-activity relationship of tetrahydrobiopterin analogs .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
