14231-41-5
14231-41-5
Chemical Structure
Tetrahydroaminopterin
Synonym(s): NSC 524120
- CAS No.: 14231-41-5
- Formula:C19H24N8O5
- Molecular Weight:444.44
IUPAC Name: (4-(((2,4-diamino-1,5,6,7-tetrahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid
InChIKey: IQOVRBYGMACLKN-KIYNQFGBSA-N
SMILES: O=C(CC[C@H](NC(C1=CC=C(C=C1)NCC2NC3=C(N=C(NC3=NC2)N)N)=O)C(O)=O)O
Biological Activity: Tetrahydroaminopterin (NSC 524120) is a tetrahydropteridine analog and the tetrahydro-reduced derivative of aminopterin. Tetrahydroaminopterin is used for studies on phenylalanine hydroxylase cofactor binding and the structure-activity relationship of tetrahydrobiopterin analogs[1].
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Tetrahydroaminopterin | Tetrahydroaminopterin (NSC 524120) is a tetrahydropteridine analog and the tetrahydro-reduced derivative of aminopterin. Tetrahydroaminopterin is used for studies on phenylalanine hydroxylase cofactor binding and the structure-activity relationship of tetrahydrobiopterin analogs. | |||||||||||||||||||||
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