2,4-Diamino-6-hydroxypyrimidine (Standard)
2,4-Diamino-6-hydroxypyrimidine (Standard) is the analytical standard of 2,4-Diamino-6-hydroxypyrimidine. This product is intended for research and analytical applications. 2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis). 2,4-Diamino-6-hydroxypyrimidine blocks Tetrahydrobiopterin (BH4) synthesis and suppresses NO production.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 56-06-4
- Formula: C4H6N4O
- Molecular Weight:126.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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HY-100954
2,4-Diamino-6-hydroxypyrimidine
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HY-100965
Diphenyleneiodonium chloride
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HY-102015
6-Biopterin
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HY-N0091
Hypoxanthine
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HY-102015R
6-Biopterin (Standard)
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HY-W017389
Xanthine
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HY-18731
1400W Dihydrochloride
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HY-18734A
Carboxy-PTIO potassium
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HY-12116
L-NIL
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HY-100986
L-NIO dihydrochloride
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HY-N0091R
Hypoxanthine (Standard)
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 56-06-4
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Molecular Weight 126.12
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Formula C4H6N4O
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SMILES
O=C1N=C(N)NC(N)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Sung YJ, et al. 2,4-Diamino-6-hydroxypyrimidine, an inhibitor of GTP cyclohydrolase I, suppresses nitric oxide production by chicken macrophages. Int J Immunopharmacol. 1994 Feb;16(2):101-8. [Content Brief]
[2]. Kazuhisa Ikemoto, et al. 2,4-Diamino-6-hydroxypyrimidine (DAHP) suppresses cytokine-induced VCAM-1 expression on the cell surface of human umbilical vein endothelial cells in a BH(4)-independent manner. Biochim Biophys Acta. Jul-Aug 2008;1780(7-8):960-5. [Content Brief]
[3]. T Kobayashi, et al. Gastrointestinal serotonin: depletion due to tetrahydrobiopterin deficiency induced by 2,4-diamino-6-hydroxypyrimidine administration. J Pharmacol Exp Ther. 1991 Feb;256(2):773-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2,4-Diamino-6-hydroxypyrimidine (Standard) Related Classifications
HY-100954R Related Classifications
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