5 Results for "

threshold pressure

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "threshold pressure" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-14218
CAS No.: 97-39-2
Purity:  99.66%
Synonyms: 1,3-Di-o-tolylguanidine; DTG
Target:  

Sigma Receptor

Research Areas:  

Neurological Disease

Ditolylguanidine (1,3-Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor) with Ki values of 69 and 21 nM for σ1 and σ2 receptors, respectively. Ditolylguanidine effectively inhibits the growth of small cell lung cancer cells. Ditolylguanidine can be used for the research of lung cancer .
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Cat. No.: HY-120496
CAS No.: 1204178-50-6
Synonyms: ASP3662
Target:  

11β-HSD

Clofutriben (ASP3662) is a selective, orally active and brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with Ki values of 5.3 nM (human), 2.6 nM (mouse), and 23 nM (rat). Clofutriben inhibits conversion of inactive glucocorticoids to active glucocorticoids, reducing intracellular glucocorticoid exposure. Clofutriben ameliorates neuropathic pain, and restores muscle pressure thresholds in rodent models, while lacking effects in inflammatory pain .
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Cat. No.: HY-14218R
CAS No.: 97-39-2
Synonyms: 1,3-Di-o-tolylguanidine (Standard); DTG (Standard)
Research Areas:  

Neurological Disease

Ditolylguanidine (Standard) is the analytical standard of Ditolylguanidine. This product is intended for research and analytical applications. Ditolylguanidine (1,3-Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor) with Ki values of 69 and 21 nM for σ1 and σ2 receptors, respectively. Ditolylguanidine effectively inhibits the growth of small cell lung cancer cells. Ditolylguanidine can be used for the research of lung cancer .
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Cat. No.: HY-W277805
CAS No.: 549-68-8
Octaverine is a synthetic isoquinoline alkaloid with oral activity and adrenergic lytic activity. Octaverine antagonizes the pressor effect of adrenaline, elevates the toxicity threshold of adrenaline, and reduces blood pressure. Octaverine increases respiratory depth, respiratory frequency, ventilation rate, and coronary blood flow. Octaverine inhibits spontaneous uterine contractions, antagonizes induced intestinal spasms, alleviates histamine-induced bronchospasm, and exhibits favorable biosafety. Octaverine can be used in research related to intestinal spasms and bronchospasm .
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Cat. No.: HY-P1336A
CAS No.: 2952824-50-7
Synonyms: Deltorphin 1 TFA; Deltorphin C TFA; [D-Ala2] Deltorphin I TFA
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Deltorphin I TFA (Deltorphin 1 TFA; Deltorphin C TFA; [D-Ala2] Deltorphin I TFA) is a high-affinity, selective δ-opioid receptor agonist that targets the δ1 and δ2 opioid receptor subtypes. Deltorphin I TFA produces analgesic effects in the rat spinal cord. Deltorphin I TFA increases the pain threshold in rats. Deltorphin I TFA can be used in studies related to nociception (acute pain) .
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