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titration

" in MedChemExpress (MCE) Product Catalog:

34

Inhibitors & Agonists

5

Fluorescent Dyes

12

Biochemical Assay Reagents

2

Peptides

1

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1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0040
    Calcein
    10+ Cited Publications

    Fluorexon

    		 Fluorescent Dye Others
    Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
    Calcein
  • HY-13963
    ZCL278
    3 Publications Verification

    		 Ras Dengue Virus VSV Arenavirus Infection Neurological Disease Metabolic Disease Cancer
    ZCL278 is a selective Cdc42 inhibitor with Kds of 6.4 μM in fluorescence titration and 11.4 μM in surface plasmon resonance (SPR) measurement. ZCL278 is able to disrupt the Cdc42-ITSN interaction as well as GTP/GDP binding. ZCL278 has inhibitory effects on various enveloped viruses, but is ineffective against non-enveloped viruses. ZCL278 can be used for the studies of arsenic neurotoxicity and HER2-positive gastric cancer (GC) .
    ZCL278
  • HY-Y0699
    Methyl red

    		Environmental Pollutants Fluorescent Dye Others
    Methyl red is a pH-sensitive acid-base indicator and colorimetric reagent with a pKa of 5.1. Methyl red achieves visual judgment of the titration endpoint through reversible structural changes of protonation (red, pH <4.4) and deprotonation (yellow, pH >6.2). Methyl red is widely used in acid-base titration in chemical analysis and buffer pH monitoring in biochemistry .
    Methyl red
  • HY-W110910
    Eriochrome black T, Indicator

    		Biochemical Assay Reagents Infection
    Eriochrome black T, Indicator is a complexing agent for metal ions (e.g., Ca 2+, Mg 2+) and is used as an indicator in complexometric titrations. Eriochrome black T, Indicator forms colored complexes with metal ions through covalent coordination bonds, and indicates the endpoint of the titration by color change. Eriochrome black T, Indicator can be used as an anionic azo dye in photocatalytic degradation studies to evaluate the performance of photocatalysts. The reaction solution of Eriochrome black T, Indicator combined with Mg 2+ is initially purple. During loop-mediated isothermal amplification (LAMP), the color changes from purple to sky blue due to the consumption of Mg 2+ by the formation of magnesium pyrophosphate, indicating a positive reaction. The optimal concentration of Eriochrome black T, Indicator in LAMP is 60 μM, and the detection limit for Mycobacterium tuberculosis is 1 pg DNA/reaction .
    Eriochrome black T, Indicator
  • HY-W110794
    Crystal violet, IND (0.0-2.0)

    		Environmental Pollutants Biochemical Assay Reagents Others
    Crystal violet, IND (0.0-2.0) is a specialized indicator suitable for strongly acidic systems, which reflects changes in pH within the range of 0.0-2.0 through color changes. Crystal violet, IND (0.0-2.0) is widely used in acid-base titration, chemical analysis, and industrial testing fields .
    Crystal violet, IND (0.0-2.0)
  • HY-D0874
    HEPPSO

    		Biochemical Assay Reagents Others
    HEPPSO is a zwitterionic Good's buffer suitable for physiological pH conditions. HEPPSO forms high-order oligomers in aqueous solutions and can form a 1:1 complex with Cu 2+ via its hydroxyalkyl and tertiary amine groups. However, HEPPSO contains a structurally similar trace impurity lacking an alkanesulfonic acid side chain. The complex formed by this impurity and Cu 2+ has a very low Ka; therefore, HEPPSO may interfere with studies on copper speciation analysis in natural water bodies .
    HEPPSO
  • HY-125929
    Murexide

    Ammonium purpurate

    		 Biochemical Assay Reagents Others
    Murexide (Ammonium purpurate) can be used as an indicator in complexometric titrations to determine water hardness.
    Murexide
  • HY-125457
    α-Naphtholbenzein

    p-Naphtolbenzein

    		 Biochemical Assay Reagents Others
    α-Naphtholbenzein (p-Naphtolbenzein) is a dye. α-Naphtholbenzein can be used as a pH indicator. α-Naphtholbenzein is commonly used in experiments such as acid-base neutralization reactions, titration, and pH measurement .
    α-Naphtholbenzein
  • HY-Y1374
    Benzoic anhydride

    		Biochemical Assay Reagents Others
    Benzoic anhydride is a catalyst that can be used for organic synthesis reactions. Benzoic anhydride is used as a chemical titration reagent for selective quantification and deactivation of phenolic hydroxyl groups on the surface of carbon nanotubes .
    Benzoic anhydride
  • HY-W006212
    1,4,7-Triazonane

    1,4,7-Triazacyclononane

    		 Biochemical Assay Reagents Others
    1,4,7-Triazonane (1,4,7-Triazacyclononane), an intermediate in the synthesis of 1,4,7-trifunctionalized derivatives, is a possible reagent for compleximetric titrations with high cation-binding selectivity .
    1,4,7-Triazonane
  • HY-N2054
    Kaempferol 4'-glucoside

    Kaempferol 4'-β-glucoside

    		 Drug Derivative Others
    Kaempferol 4'-glucoside (Kaempferol 4'-β-glucoside) is a glycosylated form of Kaempferol (HY-14590). Kaempferol 4'-glucoside interacts with SBE-β-CD (HY-17031). Kaempferol 4'-glucoside can be used in the food and active compound industries .
    Kaempferol 4'-glucoside
  • HY-124493
    Aluminon
    3 Publications Verification

    ATA; Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium

    		 Biochemical Assay Reagents Others
    Aluminon (ATA; Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium) is a complexometric titration indicator and can also be used as a nuclease inhibitor affecting transfection. Aluminon is a kind of biological materials or organic compounds that are widely used in life science research .
    Aluminon
  • HY-P4668
    Valylleucine

    Val-Leu; H-Val-Leu-OH

    		 Bacterial Infection
    Valylleucine (Val-Leu; H-Val-Leu-OH) is a branched-chain dipeptide that can enter cells independently via bacterial dipeptide transport systems, and is hydrolyzed by dipeptidases to release Val and Leu. Valylleucine, as a model peptide, has its α-amino pK determined to be 7.90 by combining FDNB reaction kinetics with potentiometric titration .
    Valylleucine
  • HY-P4668A
    Valylleucine TFA

    Val-Leu TFA; H-Val-Leu-OH TFA

    		 Bacterial Infection
    Valylleucine (Val-Leu; H-Val-Leu-OH) TFA is a branched-chain dipeptide that can enter cells independently via bacterial dipeptide transport systems, and is hydrolyzed by dipeptidases to release Val and Leu. Valylleucine TFA, as a model peptide, has its α-amino pK determined to be 7.90 by combining FDNB reaction kinetics with potentiometric titration .
    Valylleucine TFA
  • HY-21170E
    Zinc trifluoromethanesulfonate

    Zinc(II) Triflate

    		 Biochemical Assay Reagents Others
    Zinc trifluoromethanesulfonate (Zinc (II) Triflate) is a Zn 2+ salt commonly used in potentiometric titration to determine the stability constants of Zn 2+-quinoline sulfonamide complexes. Aqueous solutions of Zinc trifluoromethanesulfonate form micellar structures, which result in poor desolvation kinetics of Zn 2+ and induce dendrite growth on zinc anodes, failing to support long-term cycling of zinc anodes .
    Zinc trifluoromethanesulfonate
  • HY-D2476
    H2S Fluorescent probe 1

    		Fluorescent Dye Others
    H2S Fluorescent probe 1 (Compound 2) is a fluorescent probe that detects hydrogen sulfide (H2S) with almost no cytotoxicity. Upon the addition of increasing amounts of HS - to DMSO solution of H2S Fluorescent probe 1, a new absorption peak appears gradually at 485 nm. H2S Fluorescent probe 1, the fluorescence intensity notes at 434 nm increasing rapidly by titration of HS - .
    H2S Fluorescent probe 1
  • HY-D1492
    Fast Sulphon Black F

    		Fluorescent Dye Others
    Fast Sulphon Black F is a specific copper indicator. Fast Sulphon Black F can be used for EDTA titration .
    Fast Sulphon Black F
  • HY-W110791
    Sodium diphenylamine-4-sulfonate

    		Biochemical Assay Reagents Others
    Sodium diphenylamine-4-sulfonate is a chemical indicator commonly used in redox titrations. Its reduced state is colorless and its oxidized state is reddish-purple. Sodium diphenylamine-4-sulfonate is also a quencher and reducing agent. Sodium diphenylamine-4-sulfonate inhibits the electrochemiluminescence of the ruthenium tris(bipyridine) system through energy transfer. Sodium diphenylamine-4-sulfonate participates in the synthesis of nanocrystals .
    Sodium diphenylamine-4-sulfonate
  • HY-D0277
    Eriochrome black T

    		Fluorescent Dye
    Eriochrome black T is a complex indicator used in complex titrations, e.g.
    Eriochrome black T
  • HY-Y0449C
    Ammonium thiocyanate, 99.99% trace metals basis

    Ammonium rhodanide, 99.99% trace metals basis

    		 Biochemical Assay Reagents Others
    Ammonium thiocyanate, 99.99% trace metals basis is widely used in titration methods to determine the concentrations of various metal ions (especially iron and silver) by forming distinctly different complexes.
    Ammonium thiocyanate, 99.99% trace metals basis
  • HY-W110896
    Phthalate complexing agent [Chelation indicator]

    Phthalein Purple

    		 Biochemical Assay Reagents Others
    Phthalate complexing agent [Chelation indicator] is a class of organic compounds belonging to the category of chelation indicators. It is commonly used in analytical chemistry to detect and quantify metal ions in aqueous solutions, especially in complexometric titration. Phthalate complexing agent [Chelation indicator] works by forming stable complexes with metal ions, which can then be measured using various spectroscopic or electrochemical techniques. In addition, it also has potential applications in wastewater treatment and environmental monitoring.
    Phthalate complexing agent [Chelation indicator]
  • HY-175303
    Xanthine oxidase-IN-17

    		Xanthine Oxidase Metabolic Disease
    Xanthine oxidase-IN-17 is a potent xanthine oxidase (XOD) inhibitor with an IC50 of 298 nM and a Ki of 167 nM. Xanthine oxidase-IN-17 decreases the formation of O₂ ⁻ radical by inhibiting the catalytic activity of XOD to diminish the production of uric acid. Xanthine oxidase-IN-17 shows no cytotoxicity in AML-12 hepatocytes, while suppressing uric acid production. Xanthine oxidase-IN-17 can be used for the studies of hyperuricemia and subsequently to gout .
    Xanthine oxidase-IN-17
  • HY-Y1374R
    Benzoic anhydride (Standard)

    		Biochemical Assay Reagents Reference Standards Others
    Benzoic anhydride (Standard) is the analytical standard of Benzoic anhydride. This product is intended for research and analytical applications. Benzoic anhydride is a catalyst that can be used for organic synthesis reactions. Benzoic anhydride is used as a chemical titration reagent for selective quantification and deactivation of phenolic hydroxyl groups on the surface of carbon nanotubes .
    Benzoic anhydride (Standard)
  • HY-W025784R
    Kalibor (Standard)

    Sodium tetraphenylborate (Standard); Tetraphenylboron sodium (Standard)

    		 Reference Standards Bacterial Infection
    (Sodium tetraphenylborate; Tetraphenylboron sodium) (Standard) is the analytical standard of Kalibor (HY-W025784). This product is intended for research and analytical applications. Kalibor is a boron-based salt and antibacterial agent. Kalibor exerts activity against Neisseria meningitidis and Neisseria gonorrhoeae. Kalibor facilitates boron uptake by Neisseria meningitidis cells. Kalibor reduces bacterial burden in a mouse model of Neisseria meningitidis bacteremia. Kalibor can be used for the research of bacterial infection, such as meningococcal bacteremia .
    Kalibor (Standard)
  • HY-137871
    Phenolphthalein monophosphate dicyclohexylammonium

    		Biochemical Assay Reagents Others
    Phenolphthalein monophosphate dicyclohexylammonium is a substrate for alkaline phosphatase and is used as an indicator in various titrations and enzyme immunoassays .
    Phenolphthalein monophosphate dicyclohexylammonium
  • HY-168536
    SJ46411

    		Ligands for E3 Ligase Cancer
    SJ46411 is a potent ligand for KLHDC2, with a Kd of ~260 nM measured by isothermal titration calorimetry (SPR Kd = 0.5 μM, TR-FRET IC50 = 3.9 μM, ΔTm = 6.0 °C) .
    SJ46411
  • HY-W344380
    Tetrahydro-2,5-dioxo-3-furansulfonic acid, sodium

    		Biochemical Assay Reagents
    Tetrahydro-2,5-dioxo-3-furansulfonic acid, sodium is a chemical reagent with excellent water determination activity. Tetrahydro-2,5-dioxo-3-furansulfonic acid, sodium is widely used as a titrant in Karl Fischer titration to determine the water content in various samples. Tetrahydro-2,5-dioxo-3-furansulfonic acid, sodium has important application value in chemical analysis.
    Tetrahydro-2,5-dioxo-3-furansulfonic acid, sodium
  • HY-W419044A
    Calcein calcium potassium

    		Fluorescent Dye Others
    Calcein calcium potassium is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
    Calcein calcium potassium
  • HY-W329161
    Calcein sodium salt

    		Fluorescent Dye Others
    Calcein sodium is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
    Calcein sodium salt
  • HY-174842
    HTS05585

    		Macrophage migration inhibitory factor (MIF) Inflammation/Immunology
    HTS05585 (Compound Hit-1) is a selective macrophage migration inhibitory factor (MIF) inhibitor with a Kd value of 0.29 μM measured by microscale thermophoresis (MST) and 0.32±0.01 μM verified by isothermal titration calorimetry (ITC). HTS05585 inhibits the release of pro-inflammatory factors (TNF-α, IL-6, IL-1β) from LPS-induced macrophages. HTS05585 is promising for research of inflammation-related diseases such as sepsis .
    HTS05585
  • HY-122038
    NU-8165

    		MDM-2/p53 Cancer
    NU-8165 is an inhibitor of the MDM2-p53 protein-protein interaction with anti-tumor activity. Optimization of NU-8165 was guided by MDM2 NMR titrations, which indicated key binding interaction regions. NU-8165 activated MDM2 and p21 transcription in cell-based assays and showed modest selectivity for wild-type p53 cell lines .
    NU-8165
  • HY-182033
    ClpP agonist 1

    		Bacterial ClpP Infection
    ClpP agonist 1 is a Staphylococcus aureus ClpP (SaClpP) agonist with an EC50 of 1.44 μM, Kd values of 2.95 μM (isothermal titration calorimetry) and 18 μM (bio-layer interferometry), and a low drug resistance frequency. ClpP agonist 1 reduces bacterial load, shrinks infected area and improves histopathological outcomes in a mouse skin infection model. ClpP agonist 1 can be used for the research of Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA) skin infections .
    ClpP agonist 1
  • HY-DY1091
    Calcein (solution)

    Fluorexon (solution)

    		 Fluorescent Dye Others
    Calcein (solution) (Fluorexon (solution)) is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein cannot directly cross the intact cell membrane of a living cell, unlike Calcein-AM (HY-D0041) which is cell-permeable. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems .
    Solvent and concentration: DMSO: 2 mM
    The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
    Calcein (solution)
  • HY-13963S
    ZCL278-13C

    		Isotope-Labeled Compounds Endogenous Metabolite Infection Cancer
    ZCL278- 13C is a 13C-labeled version of ZCL278 (HY-13963). ZCL278 is a selective Cdc42 inhibitor with Kds of 6.4 μM in fluorescence titration and 11.4 μM in surface plasmon resonance (SPR) measurement. ZCL278 can disrupt the interaction between Cdc42 and ITSN, and also inhibit the binding of GTP and GDP. ZCL278 has inhibitory effects on various enveloped viruses, but is ineffective against non-enveloped viruses. ZCL278 can be used in the research of arsenic neurotoxicity and HER2-positive gastric cancer (GC) [1][2][3][4].
    ZCL278-13C

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