9 Results for "

tmem16a inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "tmem16a inhibitor" in MCE Product Catalog:

74
74 Publications Verification
Cat. No.: HY-N0822
CAS No.: 517-89-5
Synonyms: C.I. 75535; Isoarnebin 4
Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM . Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway . Shikonin decreases exosome secretion through the inhibition of glycolysis . Shikonin inhibits AIM2 inflammasome activation .
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12
12 Cited Publications
Cat. No.: HY-100611
CAS No.: 407587-33-1
Purity:  99.35%
Target:  

Chloride Channel

Research Areas:  

Inflammation/Immunology Cancer

CaCCinh-A01 is an inhibitor of both TMEM16A and calcium-activated chloride channel (CaCC) with IC50s of 2.1 and 10 μM, respectively.
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3
3 Cited Publications
Cat. No.: HY-100612
CAS No.: 552309-42-9
Purity:  ≥99.0%
Target:  

Chloride Channel

Research Areas:  

Others

T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 µM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC) .
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Cat. No.: HY-153508
CAS No.: 2098490-06-1
Target:  

Chloride Channel

Research Areas:  

Others

ANO1-IN-4 (Compound 10bm) is a reversible inhibitor for calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1) with an IC50 of 0.030 µM. ANO1-IN-4 exhibits good metabolic stability in rat liver microsomes. ANO1-IN-4 inhibits spontaneous contraction in mouse isolated ileum .
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Cat. No.: HY-N0822R
CAS No.: 517-89-5
Synonyms: C.I. 75535 (Standard); Isoarnebin 4 (Standard)
Shikonin (Standard) is the analytical standard of Shikonin. This product is intended for research and analytical applications. Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM . Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway . Shikonin decreases exosome secretion through the inhibition of glycolysis . Shikonin inhibits AIM2 inflammasome activation .
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Cat. No.: HY-118170
CAS No.: 171506-87-9
Purity:  90
Target:  

Chloride Channel

Research Areas:  

Others

T16A(inh)-C01 is an inhibitor of TMEM16A (ANO1). T16A(inh)-C01 blocks chloride channel mediated by ANO1 with an IC50 of 8.4 μM, without interfering with calcium signaling .
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Cat. No.: HY-176453
CAS No.: 28282-22-6
Synonyms: N066-0059
Target:  

Chloride Channel

Research Areas:  

Cancer

Allobetulone (N066-0059) is a TMEM16A inhibitor (IC50: 0.24 µM). Allobetulone (N066-0059) can be used in anti-cancer research .
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Cat. No.: HY-100612R
CAS No.: 552309-42-9
Research Areas:  

Others

T16Ainh-A01 (Standard) is the analytical standard of T16Ainh-A01 (HY-100612). This product is intended for research and analytical applications. T16Ainh-A01, an aminophenylthiazole, is a potent transmembrane protein 16A (TMEM16A) inhibitor, inhibiting TMEM16A-mediated chloride currents with an IC50 value of ~1 μM. TMEM16A (ANO1) functions as a calcium-activated chloride channel (CaCC) .
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Cat. No.: HY-100611R
CAS No.: 407587-33-1
CaCCinh-A01 (Standard) is the analytical standard of CaCCinh-A01 (HY-100611). This product is intended for research and analytical applications. CaCCinh-A01 is an inhibitor of both TMEM16A and calcium-activated chloride channel (CaCC) with IC50s of 2.1 and 10 μM, respectively.
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