28 Results for "

transpeptidases

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "transpeptidases" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-114336
CAS No.: 11029-12-2
Enocyanin is an anthocyanin extracted from grapes. Enocyanin shows inhibitory effect on the leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase and esterase activity .
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2
2 Cited Publications
Cat. No.: HY-W016586
CAS No.: 42228-92-2
Synonyms: AT-125; U-42126
Acivicin (AT-125), a natural product produced by Streptomyces sviceus is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties .
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2
2 Cited Publications
Cat. No.: HY-W016586A
CAS No.: 161922-40-3
Synonyms: AT-125 hydrochloride; U-42126 hydrochloride
Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties .
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1
1 Cited Publications
Cat. No.: HY-E70234
CAS No.: 9033-39-0
Synonyms: SrtA
Target:  

Bacterial

Research Areas:  

Others

Sortase A, S. aureus (SrtA), a transpeptidase enzyme is present in many Gram-positive bacteria and helps in the recruitment of the cell surface proteins. Sortase A, S. aureus plays an important part in ligation of various molecules on the cell surfaces .
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1
1 Cited Publications
Cat. No.: HY-E70234A
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

Sortase A, S. aureus (non-Ca 2+-dependent), a transpeptidase enzyme is present in many Gram-positive bacteria and helps in the recruitment of the cell surface proteins. Sortase A, S. aureus (non-Ca 2+-dependent) plays an important part in ligation of various molecules on the cell surfaces .
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1
1 Cited Publications
Cat. No.: HY-N0241
CAS No.: 85571-15-9
Rhodionin is an orally active, multifunctional antivirulence and cytoprotective agent that targets and inhibits Lipase, sortase A (SrtA), CYP2D6 (IC50=0.761 μM), AChE (IC50=2.43-57.5 μM), and DPPH free radicals (IC50=19.49 μM). Rhodionin is isolable from the roots of Rhodiola crenulata. Rhodionin reduces postprandial serum triglyceride levels in mice by inhibiting lipase activity. Rhodionin also binds directly to SrtA to inhibit its transpeptidase activity, thereby reducing the fibrinogen adhesion and surface protein A levels of MRSA, effectively inhibiting biofilm formation and protecting against MRSA-induced cell damage. Rhodionin improves the survival rate of infected mice without affecting MRSA growth, and finds wide application in studies related to hyperlipidemia, exogenous obesity, and pneumonia induced by methicillin-resistant Staphylococcus aureus (MRSA) .
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1
1 Cited Publications
Cat. No.: HY-E70234B
Target:  

Bacterial

Research Areas:  

Others

Sortase A (MS grade) is a transpeptidase of Staphylococcus aureus, which can perform site-specific cleavage or transpeptidation linkage by utilizing the LPXTG recognition sequence. Sortase A (MS grade) can be utilized in high-sensitivity mass spectrometry (MS) applications and chemical enzymatic protein labeling.
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Cat. No.: HY-113110
CAS No.: 19246-18-5
Purity:  99.96%
Synonyms: L-Cysteinylglycine; Cys-Gly; H-Cys-Gly-OH
Cysteinylglycine (L-Cysteinylglycine; Cys-Gly) is a dipeptide formed by the peptide bond linkage between cysteine (Cysteine) and glycine (Glycine). Cysteinylglycine is an important metabolic intermediate in the human body, mainly derived from the degradation of glutathione (GSH). Cysteinylglycine reduces ferric iron to ferrous iron, drives the redox cycle of iron, generates reactive oxygen species (ROS), stimulates oxidative reactions, induces lipid peroxidation of human plasma LDL lipoproteins, and causes oxidative damage to DNA bases. Cysteinylglycine can be used as a biomarker to evaluate ischemic heart disease, breast cancer and other conditions .
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Cat. No.: HY-W009749A
CAS No.: 535-34-2
Target:  

Drug Intermediate

Research Areas:  

Others

DL-Cystathionine is a mixture of 4 isomers of cystathionine and allocystathionine. DL-Cystathionine also is an intermediate in the biosynthesis of amino acid cysteine. DL-Cystathionine serves as a standard for quantifying tissue cystathionine .
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Cat. No.: HY-N13356
CAS No.: 5652-48-2
Synonyms: gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr
L-gamma-Glutamyl-L-threonine (gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr) is a dipeptide obtained through the formal condensation of the L-glutamic acid side chain carboxyl group and the L-threonine amino group. L-gamma-Glutamyl-L-threonine is present in high concentrations in human urine and exhibits antibacterial activity against Gram-negative bacterial. L-gamma-Glutamyl-L-threonine is also a flavor compound. Gamma-Glutamylthreonine is a metabolite catalyzed by γ-glutamyl transpeptidase and is associated with immune regulation. Gamma-Glutamylthreonine can be used in research on inflammation and bacterial infections .
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Cat. No.: HY-P5481
CAS No.: 1807943-24-3
Target:  

Peptides

Research Areas:  

Others

DABCYL-LPETG-EDANS is a biological active peptide. (This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.)
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Cat. No.: HY-171995
CAS No.: 2369899-34-1
Synonyms: Rotor NO.4 TFA
Research Areas:  

Infection

Rf470 (Rotor NO.4) TFA is a FMR-probe-D-lysine conjugate (Max Ex: 470 nM; Max Em: 640 nM) that can be covalently incorporated into peptidoglycan by bacteria. Rf470 TFA has extremely weak fluorescence in the free state, but its fluorescence is significantly enhanced when it is catalytically incorporated into peptidoglycan by transpeptidases. Through fluorescence changes, Rf470 TFA can be used for real-time monitoring of peptidoglycan biosynthesis, detection of transpeptidase activity, and screening of antibiotics, etc .
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Cat. No.: HY-126710
CAS No.: 519170-13-9
Purity:  98.83%
Research Areas:  

Cancer

OU749 is a potent γ-glutamyl transpeptidase (GGT) inhibitor with a Ki value of 17.6 µM. OU749 shows cytotoxicity .
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Cat. No.: HY-113456S
CAS No.: 1240398-17-7
Purity:  98.4%
Leukotriene D4-d5 is the deuterium labeled Leukotriene D4. Leukotriene D4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. Leukotriene D4 is the first cysteinyl-leukotriene metabolite of LTC4. Leukotriene D4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute hypersensitivity.
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Cat. No.: HY-146343
BMI-Glu is a selective γ-glutamyl transpeptidase (GGT) fluorescent probe with a Km of 69.63 µM. BMI-Glu has high sensitivity, good water solubility and biocompatibility .
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Cat. No.: HY-W016586AR
CAS No.: 161922-40-3
Synonyms: AT-125 hydrochloride (Standard); U-42126 hydrochloride (Standard)
Acivicin (hydrochloride) (Standard) is the analytical standard of Acivicin (hydrochloride). This product is intended for research and analytical applications. Acivicin hydrochloride (AT-125 hydrochloride), a natural product produced by Streptomyces sviceus, is a γ-glutamyl transpeptidase (GGT) inhibitor. Acivicin hydrochloride can across the blood-brain barrier and has anti-cancer, anti-parasitic properties[1][2].
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Cat. No.: HY-100500
CAS No.: 80734-02-7
Purity:  98.96%
Synonyms: KBT 1585 hydrochloride
Lenampicillin hydrochloride (KBT 1585 hydrochloride) is an orally active proagent of Ampicillin and is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins (transpeptidase). Lenampicillin hydrochloride has improved absorption and decreased side effects compares to Ampicillin and is applied in the investigation of the suppurative skin and soft tissue infection .
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Cat. No.: HY-W016586R
CAS No.: 42228-92-2
Synonyms: AT-125 (Standard); U-42126 (Standard)
Articaine (Standard) is the analytical standard of Articaine. This product is intended for research and analytical applications. Articaine (Hoe-045 free base) is an amide agent that can suppress or relieve pain. containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine ameliorates LPS-induced acute kidney injury via inhibition of NF-κB activation and the NLRP3 inflammasome pathway .
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Cat. No.: HY-N17582
CAS No.: 1526987-82-5
(7S,8S)-Dihydrodehydrodiconiferyl alcohol 9’-β-D-glucopyranoside is a Streptococcus mutans Sortase A inhibitor with an IC50 of 37.3 μM. (7S,8S)-Dihydrodehydrodiconiferyl alcohol 9’-β-D-glucopyranoside inhibits transpeptidase activity linked to Gram-positive bacterial surface protein anchoring. (7S,8S)-Dihydrodehydrodiconiferyl alcohol 9’-β-D-glucopyranoside can be used for the research of dental caries .
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Cat. No.: HY-207462
CAS No.: 2114983-08-1
Target:  

Bacterial

Research Areas:  

Infection

CBA-4 is an L,D-transpeptidase inhibitor. CBA-4 covalently acylates the active site of L,D-transpeptidase to form a stable acylenzyme adduct. CBA-4 can be used for research on bacterial resistance .
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