OU749
Based on 1 Customer Validation
OU749 is a potent γ-glutamyl transpeptidase (GGT) inhibitor with a Ki value of 17.6 µM. OU749 shows cytotoxicity.
For research use only. We do not sell to patients.
- Purity: 98.83%
- CAS No.: 519170-13-9
- Formula: C16H15N3O3S2
- Molecular Weight:361.44
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Ki: 17.6 µM (GGT)[1]
OU749 (compound 3) (3 days) shows cytotoxicity with an LD50 value of 128 µM for 786-O cells[1].
OU749 (0-1000 µM) inhibits GGT (γ-glutamyl transpeptidase) activity in a dose-dependent manner in 786-O and HK-2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 519170-13-9
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Appearance Solid
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Molecular Weight 361.44
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Formula C16H15N3O3S2
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Color White to off-white
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SMILES
O=S(C1=CC=CC=C1)(NC2=NN=C(CC3=CC=C(OC)C=C3)S2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (345.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7667 mL | 13.8336 mL | 27.6671 mL | 69.1678 mL |
| 5 mM | 0.5533 mL | 2.7667 mL | 5.5334 mL | 13.8336 mL | |
| 10 mM | 0.2767 mL | 1.3834 mL | 2.7667 mL | 6.9168 mL | |
| 15 mM | 0.1844 mL | 0.9222 mL | 1.8445 mL | 4.6112 mL | |
| 20 mM | 0.1383 mL | 0.6917 mL | 1.3834 mL | 3.4584 mL | |
| 25 mM | 0.1107 mL | 0.5533 mL | 1.1067 mL | 2.7667 mL | |
| 30 mM | 0.0922 mL | 0.4611 mL | 0.9222 mL | 2.3056 mL | |
| 40 mM | 0.0692 mL | 0.3458 mL | 0.6917 mL | 1.7292 mL | |
| 50 mM | 0.0553 mL | 0.2767 mL | 0.5533 mL | 1.3834 mL | |
| 60 mM | 0.0461 mL | 0.2306 mL | 0.4611 mL | 1.1528 mL | |
| 80 mM | 0.0346 mL | 0.1729 mL | 0.3458 mL | 0.8646 mL | |
| 100 mM | 0.0277 mL | 0.1383 mL | 0.2767 mL | 0.6917 mL |
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