Stk39 - serine threonine kinase 39 Gene

Also Known as Spak

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 54348

Summary

Enables protein kinase binding activity and protein serine/threonine kinase activity. Involved in positive regulation of ion transport; positive regulation of p38MAPK cascade; and protein autophosphorylation. Located in Cytoskeleton and cytosol. Is extrinsic component of membrane. Orthologous to human STK39 (serine/threonine kinase 39). [provided by Alliance of Genome Resources, Apr 2022]

Stk39 Products (1)

mRNA Protein Name
NM_019362.1 NP_062235.1 STE20/SPS1-related proline-alanine-rich protein kinase
Molecular Function GO Annotation Evidence References Source
enables kinase activity IMP
IMP: Inferred from mutant phenotype
12740379 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
12740379 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
16083423 RGD
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
10980603 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of ion transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
12740379 RGD
involved in positive regulation of p38MAPK cascade IMP
IMP: Inferred from mutant phenotype
10980603 RGD
involved in positive regulation of potassium ion transport IMP
IMP: Inferred from mutant phenotype
19307180 RGD
involved in protein autophosphorylation IMP
IMP: Inferred from mutant phenotype
10980603 RGD
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
10980603 RGD
involved in protein phosphorylation IMP
IMP: Inferred from mutant phenotype
12740379 RGD
Cellular Component GO Annotation Evidence References Source
located in cell cortex IDA
IDA: Inferred from direct assay
25515571 RGD
located in cytosol IDA
IDA: Inferred from direct assay
25515571 RGD
located in cytosol IMP
IMP: Inferred from mutant phenotype
10980603 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

STE20/SPS1-related proline-alanine-rich protein kinase

  • PS/TK

  • PSTK1

  • Ste-20 related kinase

  • pancreatic serine/threonine-protein kinase

  • serine/threonine-protein kinase 39

  • ste-20-related kinase

Orthologs Information

Species Symbol Source ID
Homo sapiens Stk39 NCBI NCBI:27347