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Cat. No.: HY-114800

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Soporidine

Name: Soporidine
Brand: MedChemExpress
SKU: HY-114800
Availability: PreOrder

(Synonyms: RG4; SOP)

Soporidine is an antagonist of germination of the parasitic plant Striga hermonthica. Soporidine specifically inhibits a S. hermonthica strigolactone receptor and inhibits the parasite's germination. Soporidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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CAS No.: 1060376-43-3
Formule: C₂₇H₃₀F₃NO₃
Masse moléculaire:473.53

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Soporidine Chemical Structure

CAS No.: 1060376-43-3

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Activité biologique
- Description
- In Vitro
- Essai clinique
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
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Activité biologique

Description

Soporidine is an antagonist of germination of the parasitic plant Striga hermonthica. Soporidine specifically inhibits a S. hermonthica strigolactone receptor and inhibits the parasite's germination^[1]. Soporidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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In Vitro

Soporidine binds to the AtHTL receptor and to a key Strigolactone (SL) receptor in S. hermonthica, inhibiting Striga germination in the presence of SLs. Soporidine could serve as the basis for the development of Strigolactone (SL) antagonist to combat Striga infestations. Soporidine is a potent antagonist in GR24-dependent Arabidopsis germination assay and shows no enhancement of SL signaling mutant phenotypes^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 1060376-43-3
Masse moléculaire 473.53
Formule C₂₇H₃₀F₃NO₃
SMILES

O=C(OCC)C1(CCN(CC1)CC2=CC=C(C=C2)C#CCCO)CC3=CC=CC(C(F)(F)F)=C3
Synonyms

RG4; SOP
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Duncan Holbrook-Smith, et al. Small-molecule antagonists of germination of the parasitic plant Striga hermonthica. Nat Chem Biol. 2016 Sep;12(9):724-9. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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