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Symphytine 

Cat. No.: HY-122927
Handling Instructions

Symphytine is a pyrrolizidine alkaloid isolated from Symphytum officinale and has carcinogenicity.

For research use only. We do not sell to patients.

Symphytine Chemical Structure

Symphytine Chemical Structure

CAS No. : 22571-95-5

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Description

Symphytine is a pyrrolizidine alkaloid isolated from Symphytum officinale and has carcinogenicity[1].

In Vivo

Symphytine (intraperitoneal injection; 13 mg/kg; 330 days) leads to survival for more than 330 days after the start of injections. Four of 20 rats (20%) had liver tumors: three has hemangioendothelial sarcoma and 1 has liver cell adenoma[1].

Animal Model: Male inbred ACI rats[1]
Dosage: 13 mg/kg
Administration: Intraperitoneal injection; 330 days
Result: Led to hepatic tumor in rats.
Molecular Weight

381.46

Formula

C₂₀H₃₁NO₆

CAS No.

22571-95-5

SMILES

C/C=C(C)/C(O[[email protected]]1[[email protected]@]2([H])C(COC([[email protected]@](C(C)C)(O)[[email protected]@H](O)C)=O)=CCN2CC1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

SymphytineOthersHepaticTumorcarcinogenicityadenomapyrrolizidine alkaloidInhibitorinhibitorinhibit

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