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Cat. No.: HY-122927
Handling Instructions

Symphytine is a pyrrolizidine alkaloid isolated from Symphytum officinale and has carcinogenicity.

For research use only. We do not sell to patients.

Symphytine Chemical Structure

Symphytine Chemical Structure

CAS No. : 22571-95-5

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Symphytine is a pyrrolizidine alkaloid isolated from Symphytum officinale and has carcinogenicity[1].

In Vivo

Symphytine (intraperitoneal injection; 13 mg/kg; 330 days) leads to survival for more than 330 days after the start of injections. Four of 20 rats (20%) had liver tumors: three has hemangioendothelial sarcoma and 1 has liver cell adenoma[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male inbred ACI rats[1]
Dosage: 13 mg/kg
Administration: Intraperitoneal injection; 330 days
Result: Led to hepatic tumor in rats.
Molecular Weight





C/C=C(C)/C(O[[email protected]]1[[email protected]@]2([H])C(COC([[email protected]@](C(C)C)(O)[[email protected]@H](O)C)=O)=CCN2CC1)=O


Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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