2. Neuronal Signaling
  3. Tau Protein
  4. Tau ligand-2

Tau ligand-2 is a tau aggregate ligand with a Ki value of 0.99 nM. Radiolabeled (18F) Tau ligand-2 serves as a PET tracer. Tau ligand-2 is applicable to research related to Alzheimer's disease.

For research use only. We do not sell to patients.

Tau ligand-2

Tau ligand-2 Chemical Structure

CAS No. : 3046416-94-5

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Tau ligand-2 Related Antibodies

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Description

Tau ligand-2 is a tau aggregate ligand with a Ki value of 0.99 nM. Radiolabeled (18F) Tau ligand-2 serves as a PET tracer. Tau ligand-2 is applicable to research related to Alzheimer's disease[1].

Parmacokinetics
Species Dose Route Cmax AUC0-∞ MRT T1/2 V CL
Rat[1] 0.3 mg/kg i.v. 43.93 ng/mL 19.40 ng·h/mL 0.40 h 0.35 h 7821.85 mL/kg 15343.63 mL/h/kg
In Vivo

Tau ligand-2 (Compound 28) (0.3 mg/kg; intravenous administration; single dose) exhibits rapid pharmacokinetic properties in rats, making it suitable for development as a central nervous system PET tracer[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

228.23

Formula

C12H9FN4
CAS No.
SMILES

FC1=CC(NC2=CC=CN3C=CN=C23)=NC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Tau ligand-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tau ligand-23046416-94-5Tau ligand2Tau ligand 2Tau Proteintau aggregatesADInhibitorinhibitorinhibit

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