Tetrahydro-β-carboline
Based on 1 Customer Validation
Tetrahydro-β-carboline (Tryptoline) is a metabolite of tryptamine, also is a competitive serotonin reuptake inhibitor with an Ki value of 6.1 µM.
For research use only. We do not sell to patients.
- Purity: 99.40%
- CAS No.: 16502-01-5
- Formula: C11H12N2
- Molecular Weight:172.23
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Biological Activity
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serotonin 6.1 μM (Ki) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:180-200g female Sprague-Dawley rats[1]
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Dosage:20 µg
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Administration:Intraventricular injection
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Result:Increased of serotonin levels in the same part of the brain whereas the monoamine oxidase activity was not altered.
Chemical Information
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CAS No. 16502-01-5
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Appearance Solid
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Molecular Weight 172.23
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Formula C11H12N2
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Color Light yellow to brown
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SMILES
C1(NC2=C3CCNC2)=C3C=CC=C1
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Synonyms
Tryptoline
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (580.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.8062 mL | 29.0309 mL | 58.0619 mL | 145.1547 mL |
| 5 mM | 1.1612 mL | 5.8062 mL | 11.6124 mL | 29.0309 mL | |
| 10 mM | 0.5806 mL | 2.9031 mL | 5.8062 mL | 14.5155 mL | |
| 15 mM | 0.3871 mL | 1.9354 mL | 3.8708 mL | 9.6770 mL | |
| 20 mM | 0.2903 mL | 1.4515 mL | 2.9031 mL | 7.2577 mL | |
| 25 mM | 0.2322 mL | 1.1612 mL | 2.3225 mL | 5.8062 mL | |
| 30 mM | 0.1935 mL | 0.9677 mL | 1.9354 mL | 4.8385 mL | |
| 40 mM | 0.1452 mL | 0.7258 mL | 1.4515 mL | 3.6289 mL | |
| 50 mM | 0.1161 mL | 0.5806 mL | 1.1612 mL | 2.9031 mL | |
| 60 mM | 0.0968 mL | 0.4838 mL | 0.9677 mL | 2.4192 mL | |
| 80 mM | 0.0726 mL | 0.3629 mL | 0.7258 mL | 1.8144 mL | |
| 100 mM | 0.0581 mL | 0.2903 mL | 0.5806 mL | 1.4515 mL |
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