TM5007
TM5007 is a poent and orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) with an IC50 of 29 μM. TM5007 enhance fibrinolysis activity and inhibits coagulation. TM5007 also prevents the fibrotic process initiated by bleomycin in mouse lung.
For research use only. We do not sell to patients.
- CAS No.: 342595-05-5
- Formula: C24H20N2O6S4
- Molecular Weight:560.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 342595-05-5
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Molecular Weight 560.69
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Formula C24H20N2O6S4
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SMILES
O=C(NC1=C(C(O)=O)C(C2=CC=CS2)=CS1)CCCCC(NC3=C(C(O)=O)C(C4=CC=CS4)=CS3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)