TP-DEA2
TP-DEA2, a predictable-release Triptolide (HY-32735) prodrug, block Bleomycin-induced pulmonary fibrosis and inflammation. TP-DEA2 significantly inhibits α-SMA production.
For research use only. We do not sell to patients.
- CAS No.: 2871739-84-1
- Formula: C25H34N2O7
- Molecular Weight:474.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
TP-DEA2 converts to Triptolide (TP) autonomously without the involvement of enzymes[1].
TP-DEA2 can inhibit the expression of a disintegrin and metalloproteinase 10 (ADAM 10) induced by TGF-β1 and reduce the secretion of a-SMA in fibroblasts[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2871739-84-1
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Molecular Weight 474.55
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Formula C25H34N2O7
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SMILES
C[C@@]12[C@@]34[C@]5([C@@H]([C@@]6([C@](O6)([H])[C@]3([H])O4)C(C)C)OC(N(C)CCNC)=O)[C@@](C[C@@]1([H])C7=C(C(OC7)=O)CC2)([H])O5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TP-DEA2 Related Classifications
HY-162929 Related Classifications
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