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  2. TRFS-red

TRFS-red 

Cat. No.: HY-D1251
Handling Instructions

TRFS-red, a red fluorescence emission off-on probe, is selective for thioredoxin reductase (TrxR). TRFS-red exhibits high response rate and sensitivity. TRFS-red can be used for imaging live cells.

For research use only. We do not sell to patients.

TRFS-red Chemical Structure

TRFS-red Chemical Structure

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Description

TRFS-red, a red fluorescence emission off-on probe, is selective for thioredoxin reductase (TrxR). TRFS-red exhibits high response rate and sensitivity. TRFS-red can be used for imaging live cells[1].

In Vitro

TRFS-red (1 μM; 30-120 min) gives red fluorescence signal in live HeLa cells, and the red fluorescence is predominantly distributed in the cytosol[1].
TRFS-red (10 μM) has a maximal absorption at ~530 nm in TE buffer (50 mM Tris-HCl and 1 mM EDTA, pH 7.4)[1].
TRFS-red displays a reliable fluorescence signal in the pH range of 5.5-8.5[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

682.12

Formula

C₂₈H₂₈ClN₃O₁₁S₂

SMILES

O=C(NC1=CC2=C(N=C3C(O2)=C/C(C=C3)=[N+](CCC(OC)=O)/CCC(OC)=O)C4=C1C=CC=C4)OC5CSSC5.O=Cl(=O)([O-])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

TRFS-redOthersredfluorescenceemissionoff-onprobethioredoxinreductaseTrxRimaginglivecellsInhibitorinhibitorinhibit

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TRFS-red
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HY-D1251
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