TYT-1
TYT-1 is a sulfonamide-thiourea compound that has inhibitory activity against West Nile virus replication with a 50% effective concentration of 0.7 microM, blocking a post-entry, pre-assembly step of viral replication.
For research use only. We do not sell to patients.
- CAS No.: 64803-10-7
- Formula: C21H17N3O2S3
- Molecular Weight:439.57
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Vero | CC50 |
>70 μM
Compound: TYT-1
|
Cytotoxicity against african green monkey Vero cells after 48 hrs by MTS method
Cytotoxicity against african green monkey Vero cells after 48 hrs by MTS method
|
[PMID: 17452483] |
| Vero | CC50 |
>70 μM
Compound: TYT-1
|
Cytotoxicity against african green monkey Vero cells by trypan blue exclusion assay
Cytotoxicity against african green monkey Vero cells by trypan blue exclusion assay
|
[PMID: 17452483] |
| Vero | EC50 |
0.7 μM
Compound: TYT-1
|
Antiviral activity against West Nile virus NY 1999 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
Antiviral activity against West Nile virus NY 1999 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
|
[PMID: 17452483] |
| Vero | EC50 |
7 μM
Compound: TYT-1
|
Antiviral activity against Japanese encephalitis virus SA14-2-8 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
Antiviral activity against Japanese encephalitis virus SA14-2-8 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
|
[PMID: 17452483] |
Chemical Information
-
CAS No. 64803-10-7
-
Molecular Weight 439.57
-
Formula C21H17N3O2S3
-
SMILES
S=C(N(C1=CC=CC=C1)C2=CC=CC=C2)/N=C(N3C4=CC=CC=C4)\SCS3(=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TYT-1 Related Classifications
HY-122196 Related Classifications
Powered by Bioz