TYT-1
TYT-1 is a sulfonamide-thiourea compound that has inhibitory activity against West Nile virus replication with a 50% effective concentration of 0.7 microM, blocking a post-entry, pre-assembly step of viral replication.
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- CAS No.: 64803-10-7
- Formule: C21H17N3O2S3
- Masse moléculaire:439.57
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | CC50 |
>70 μM
Compound: TYT-1
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Cytotoxicity against african green monkey Vero cells after 48 hrs by MTS method
Cytotoxicity against african green monkey Vero cells after 48 hrs by MTS method
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[PMID: 17452483] |
| Vero | CC50 |
>70 μM
Compound: TYT-1
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Cytotoxicity against african green monkey Vero cells by trypan blue exclusion assay
Cytotoxicity against african green monkey Vero cells by trypan blue exclusion assay
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[PMID: 17452483] |
| Vero | EC50 |
0.7 μM
Compound: TYT-1
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Antiviral activity against West Nile virus NY 1999 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
Antiviral activity against West Nile virus NY 1999 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
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[PMID: 17452483] |
| Vero | EC50 |
7 μM
Compound: TYT-1
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Antiviral activity against Japanese encephalitis virus SA14-2-8 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
Antiviral activity against Japanese encephalitis virus SA14-2-8 infected in african green monkey Vero cells assessed as reduction of virus yield relative to control
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[PMID: 17452483] |
Chemical Information
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CAS No. 64803-10-7
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Masse moléculaire 439.57
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Formule C21H17N3O2S3
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SMILES
S=C(N(C1=CC=CC=C1)C2=CC=CC=C2)/N=C(N3C4=CC=CC=C4)\SCS3(=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TYT-1 Related Classifications
HY-122196 Related Classifications
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