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Zalunfiban dihydrochloride (Synonyms: RUC-4 dihydrochloride)

Cat. No.: HY-119350B Purity: 96.52%
Handling Instructions

Zalunfiban (RUC-4) dihydrochloride is a potent, selective platelet αIIbβ3 antagonist (IC50=45 nM). Zalunfiban dihydrochloride can be used for the research of myocardial infarction (MI).

For research use only. We do not sell to patients.

Zalunfiban dihydrochloride Chemical Structure

Zalunfiban dihydrochloride Chemical Structure

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 354 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 580 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1100 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1700 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2500 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Zalunfiban (RUC-4) dihydrochloride is a potent, selective platelet αIIbβ3 antagonist (IC50=45 nM). Zalunfiban dihydrochloride can be used for the research of myocardial infarction (MI)[1].

IC50 & Target

IC50: 45 nM (αIIbβ3)[1]

In Vivo

Zalunfiban dihydrochloride (1~3.86 mg/kg; s.c.; 24 hours) makes platelet aggregation performed[1].
Zalunfiban dihydrochloride (1~3.86 mg/kg; i.m.; 4.5 hours) leads to the onset of high-grade inhibition of platelet aggregation within 15–30 minutes that lasts from ~2 to >4.5 hours in a dose dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Cynomolgus Monkey
Dosage: 1~ 3.86 mg/kg (Pharmacokinetic Analysis)
Administration: S.c.; 24 hours
Result: Platelet aggregation was performed.
Molecular Weight

459.35

Formula

C₁₆H₂₀Cl₂N₈O₂S

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References
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Product Name:
Zalunfiban dihydrochloride
Cat. No.:
HY-119350B
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