α-Glucosidase-IN-72
α-Glucosidase-IN-72 (compound 5i) is a 2,4-dichloro-N-phenylacetamide derivative and an α-glucosidase inhibitor (IC50: 6 μM). α-Glucosidase-IN-72 does not follow Lipinski's "rule of five" and does not induce cancer.
For research use only. We do not sell to patients.
- Formula: C37H26Cl2N4O9
- Molecular Weight:741.53
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
IC50: 6 μM (α-Glucosidase)[1]
Chemical Information
-
Molecular Weight 741.53
-
Formula C37H26Cl2N4O9
-
SMILES
O=C(NC1=CC=C(Cl)C=C1Cl)CN2N=NC(COC3=CC=C(C(C(C4=O)=C(O)C5=C(O4)C=CC=C5)C(C6=O)=C(O)C7=C(O6)C=CC=C7)C=C3OC)=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)