1. Stem Cell/Wnt
  2. β-catenin
  3. β-catenin-IN-37

β-catenin-IN-37 

Cat. No.: HY-115543
Handling Instructions

β-catenin-IN-37 is a selective β-Catenin/T-cell factor protein-protein interaction (β-catenin/Tcf PPI) inhibitor. β-catenin-IN-37 inhibits canonical Wnt signaling and the growth of colorectal cancer cells SW480 and HCT116 with the IC50 values of 20 μM and 31 μM, respectively.

For research use only. We do not sell to patients.

β-catenin-IN-37 Chemical Structure

β-catenin-IN-37 Chemical Structure

CAS No. : 1783856-40-5

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Description

β-catenin-IN-37 is a selective β-Catenin/T-cell factor protein-protein interaction (β-catenin/Tcf PPI) inhibitor. β-catenin-IN-37 inhibits canonical Wnt signaling and the growth of colorectal cancer cells SW480 and HCT116 with the IC50 values of 20 μM and 31 μM, respectively[1].

IC50 & Target

β-catenin-IN-37 inhibits SW480 and HCT116 with the IC50 values of 20 μM and 31 μM, respectively.

In Vitro

β-catenin-IN-37 displays Ki values of 17 μM and 18 μM forβ-catenin/Tcf PPI in FP assay and in AlphaScreen assay, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

307.27

Formula

C₁₃H₉N₉O

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
β-catenin-IN-37
Cat. No.:
HY-115543
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