1783856-40-5
1783856-40-5
Chemical Structure
β-catenin-IN-37
- CAS No.: 1783856-40-5
- Formula:C13H9N9O
- Molecular Weight:307.27
IUPAC Name: 5-(2-(2H-tetrazol-5-yl)ethyl)-5H-[1,2,5]oxadiazolo[3',4':5,6]pyrazino[2,3-b]indole
InChIKey: GQIVONMEFNDYFD-UHFFFAOYSA-N
SMILES: N1(CCC2=NNN=N2)C3=NC4=NON=C4N=C3C5=C1C=CC=C5
Biological Activity: β-catenin-IN-37 is a selective β-Catenin/T-cell factor protein-protein interaction (β-catenin/Tcf PPI) inhibitor. β-catenin-IN-37 inhibits canonical Wnt signaling and the growth of colorectal cancer cells SW480 and HCT116 with the IC50 values of 20 μM and 31 μM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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β-catenin-IN-37 | 99.13% | β-catenin-IN-37 is a selective β-Catenin/T-cell factor protein-protein interaction (β-catenin/Tcf PPI) inhibitor. β-catenin-IN-37 inhibits canonical Wnt signaling and the growth of colorectal cancer cells SW480 and HCT116 with the IC50 values of 20 μM and 31 μM, respectively. | ||||||||||||||||||||
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References
Keywords
