2-(2,6-Dioxopiperidin-3-yl)phthalimidine NMe
2-(2,6-Dioxopiperidin-3-yl)phthalimidine NMe is an E3 ligase ligand of SIAIS630121-NC (HY-159016). 2-(2,6-Dioxopiperidin-3-yl)phthalimidine NMe contains an extra methyl group on the glutarimide moiety of thalidomide, which is known to abrogate its ability to bind the E3 ligase CRBN. SIAIS630121-NC is a negative control for NAMPT degrader SIAIS630121.
For research use only. We do not sell to patients.
- CAS No.: 26581-83-9
- Formula: C14H14N2O3
- Molecular Weight:258.27
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cereblon |
Chemical Information
-
CAS No. 26581-83-9
-
Molecular Weight 258.27
-
Formula C14H14N2O3
-
SMILES
O=C1C2=C(CN1C3C(N(C)C(CC3)=O)=O)C=CC=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)