2,3-Indolobetulonic acid
2,3-Indolobetulonic acid (compound 2), a triterpenoid, is α-glucosidase inhibitor with an IC50 of 1.8 µM.
For research use only. We do not sell to patients.
- CAS No.: 905837-93-6
- Formula: C36H49NO2
- Molecular Weight:527.78
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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D-IditolFungal Metabolite
Biological Activity
Description
IC50 & Target
[1]|
Glucosidase |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
7.6 μg/mL
Compound: 7
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Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
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[PMID: 18752941] |
| DU-145 | IC50 |
8.86 μg/mL
Compound: 7
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Cytotoxicity against human DU145 cells after 72 hrs by MTT assay
Cytotoxicity against human DU145 cells after 72 hrs by MTT assay
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[PMID: 18752941] |
| HBL-100 | IC50 |
10.3 μg/mL
Compound: 7
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Cytotoxicity against human HBL100 cells after 72 hrs by MTT assay
Cytotoxicity against human HBL100 cells after 72 hrs by MTT assay
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[PMID: 18752941] |
| K562 | IC50 |
10.05 μg/mL
Compound: 7
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Cytotoxicity against human K-562 cells after 72 hrs by MTT assay
Cytotoxicity against human K-562 cells after 72 hrs by MTT assay
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[PMID: 18752941] |
| MIA PaCa-2 | IC50 |
6.7 μg/mL
Compound: 7
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Cytotoxicity against human MIA PaCa2 cells after 72 hrs by MTT assay
Cytotoxicity against human MIA PaCa2 cells after 72 hrs by MTT assay
|
[PMID: 18752941] |
| NIH3T3 | IC50 |
6.9 μg/mL
Compound: 7
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Cytotoxicity against mouse NIH3T3 cells after 72 hrs by MTT assay
Cytotoxicity against mouse NIH3T3 cells after 72 hrs by MTT assay
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[PMID: 18752941] |
| PA-1 | IC50 |
6.01 μg/mL
Compound: 7
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Cytotoxicity against human PA-1 cells after 72 hrs by MTT assay
Cytotoxicity against human PA-1 cells after 72 hrs by MTT assay
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[PMID: 18752941] |
| SW-620 | IC50 |
5.15 μg/mL
Compound: 7
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Cytotoxicity against human SW620 cells after 72 hrs by MTT assay
Cytotoxicity against human SW620 cells after 72 hrs by MTT assay
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[PMID: 18752941] |
Chemical Information
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CAS No. 905837-93-6
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Molecular Weight 527.78
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Formula C36H49NO2
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SMILES
OC([C@]12[C@@]([C@@H](CC2)C(C)=C)([H])[C@]3([H])[C@@](CC1)([C@]4([C@]([C@@]5([C@@](C(C)(C6=C(C7=CC=CC=C7N6)C5)C)([H])CC4)C)([H])CC3)C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2,3-Indolobetulonic acid Related Classifications
HY-134960 Related Classifications
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