2’-Thiouridine
Based on 1 Customer Validation
2'-Thiouridine is a key modified nucleoside at the wobble position of tRNA anticodons. 2'-Thiouridine mainly exists in tRNAs for glutamic acid, glutamine, lysine, etc., and participates in precise decoding regulation.
For research use only. We do not sell to patients.
- CAS No.: 31281-28-4
- Formula: C9H12N2O5S
- Molecular Weight:260.27
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
2'-Thiouridine ensures the specificity of codon-anticodon recognition by stabilizing the base-pairing conformation and restricting abnormal wobble pairing, thereby improving translation fidelity and efficiency[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 31281-28-4
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Appearance Solid
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Molecular Weight 260.27
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Formula C9H12N2O5S
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SMILES
O=C(C=CN1[C@H]2[C@H](S)[C@H](O)[C@@H](CO)O2)NC1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)