3,6-Dihydroxyxanthone

Name: 3,6-Dihydroxyxanthone
Brand: MedChemExpress
SKU: HY-W031510
Rating: 4.5 (1 reviews)

Cat. No.: HY-W031510 Purity: 98.0%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

3,6-Dihydroxyxanthone (compound 3) is a xanthone derivatives. 3,6-Dihydroxyxanthone (compound 3) has anticancer activity. 3,6-Dihydroxyxanthone (compound 3) can be used for cancer research.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

3,6-Dihydroxyxanthone 화학구조

CAS No. : 1214-24-0

사이즈	재고	수량

무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
250 mg	해외재고보유	Estimated Time of Arrival: December 31
500 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	해외재고보유	Estimated Time of Arrival: December 31
5 g	견적 받기
10 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

1 Publications Citing Use of MCE 3,6-Dihydroxyxanthone

•Int J Biol Macromol. 2025 Dec 3;337(Pt 1):149421. [Abstract]

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

3,6-Dihydroxyxanthone (compound 3) is a xanthone derivatives. 3,6-Dihydroxyxanthone (compound 3) has anticancer activity. 3,6-Dihydroxyxanthone (compound 3) can be used for cancer research^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
BGC-823	IC₅₀	12.9 μM Compound: Table S1, R271C2	Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 30684866]
COLO 320	IC₅₀	37.7 μM Compound: 3-19	Antiproliferative activity against human COLO320 cells after 48 hrs by CCK8 assay Antiproliferative activity against human COLO320 cells after 48 hrs by CCK8 assay	[PMID: 28376372]
HepG2	IC₅₀	61.7 μM Compound: 3-19	Antiproliferative activity against human HepG2 cells after 48 hrs by CCK8 assay Antiproliferative activity against human HepG2 cells after 48 hrs by CCK8 assay	[PMID: 28376372]
K562	IC₅₀	31.2 μM Compound: 3-19	Antiproliferative activity against human K562 cells after 48 hrs by CCK8 assay Antiproliferative activity against human K562 cells after 48 hrs by CCK8 assay	[PMID: 28376372]
MCF7	IC₅₀	91.3 μM Compound: 3-19	Antiproliferative activity against human MCF7 cells after 48 hrs by CCK8 assay Antiproliferative activity against human MCF7 cells after 48 hrs by CCK8 assay	[PMID: 28376372]
MDA-MB-231	IC₅₀	31.7 μM Compound: 3-19	Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by CCK8 assay Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by CCK8 assay	[PMID: 28376372]

In Vitro

3,6-Dihydroxyxanthone (compound 3) (3.906-1000 μg/mL; 24 hours) exhibits cytotoxic activity against WiDR and Vero cell lines with IC₅₀ values of 785.58 and 1280.9 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:	WiDR and Vero cell lines
Concentration:	3.906, 7.813, 15.625, 31.25, 62.5, 125, 250 and 500 µg/mL (WiDR cell line) 7.813, 15.625, 31.25, 62.5, 125, 250, 500 and 1000 µg/mL (Vero cell line)
Incubation Time:	24 hours
Result:	Inhibited cell activity and with IC₅₀ values of 785.58 and 1,280.9 µM for WiDR and Vero cell lines.

분자량

228.20

화학식

C₁₃H₈O₄

CAS No.

1214-24-0

Appearance

Solid

Color

White to yellow

SMILES

O=C1C2=C(OC3=C1C=CC(O)=C3)C=C(O)C=C2

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

용액&용해도

In Vitro:

DMSO : 50 mg/mL (219.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.3821 mL	21.9106 mL	43.8212 mL
5 mM	0.8764 mL	4.3821 mL	8.7642 mL
10 mM	0.4382 mL	2.1911 mL	4.3821 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.55%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (247 KB) HNMR (117 KB) RP-HPLC (201 KB)

Handling Instructions (2659 KB)

References

[1]. Miladiyah I, et, al. Biological activity, quantitative structure-activity relationship analysis, and molecular docking of xanthone derivatives as anticancer drugs. Drug Des Devel Ther. 2018 Jan 15;12:149-158.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.3821 mL	21.9106 mL	43.8212 mL	109.5530 mL
	5 mM	0.8764 mL	4.3821 mL	8.7642 mL	21.9106 mL
	10 mM	0.4382 mL	2.1911 mL	4.3821 mL	10.9553 mL
	15 mM	0.2921 mL	1.4607 mL	2.9214 mL	7.3035 mL
	20 mM	0.2191 mL	1.0955 mL	2.1911 mL	5.4777 mL
	25 mM	0.1753 mL	0.8764 mL	1.7528 mL	4.3821 mL
	30 mM	0.1461 mL	0.7304 mL	1.4607 mL	3.6518 mL
	40 mM	0.1096 mL	0.5478 mL	1.0955 mL	2.7388 mL
	50 mM	0.0876 mL	0.4382 mL	0.8764 mL	2.1911 mL
	60 mM	0.0730 mL	0.3652 mL	0.7304 mL	1.8259 mL
	80 mM	0.0548 mL	0.2739 mL	0.5478 mL	1.3694 mL
	100 mM	0.0438 mL	0.2191 mL	0.4382 mL	1.0955 mL