3-Arm PEG20000-NCO
3-Arm PEG20000-NCO is a three-armed PEG derivative. The core structure of 3-Arm PEG20000-NCO consists of three PEG chains, each terminal of which is modified with an isocyanate (-NCO) group. The isocyanate groups in 3-Arm PEG20000-NCO can undergo rapid addition reactions with molecules containing amino (-NH2) or hydroxyl (-OH) groups to form stable carbamate or urea bonds, which can be used in applications such as constructing targeted drug delivery systems and modifying nanoparticles.
For research use only. We do not sell to patients.
- Molecular Weight:20000 (Average)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
The structure of PEG-NCO comprises two key parts that work synergistically:
Isocyanate (-NCO) group: Reacts with functional groups such as amino (-NH2) or hydroxyl (-OH) groups to form stable urea or carbamate bonds.
PEG chain: Acts as a hydrophilic spacer, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 20000 (Average)
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SMILES
O=C(NCCCCCCN=C=O)OCCOCC(COCCOC(NCCCCCCN=C=O)=O)(CC)COCCOC(NCCCCCCN=C=O)=O.[n].[n].[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3-Arm PEG20000-NCO Related Classifications
HY-W1049017C Related Classifications
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