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Art. -Nr.: HY-W1049017A

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3-arm PEG5000-NCO

3-Arm PEG5000-NCO is a three-armed PEG derivative. The core structure of 3-Arm PEG5000-NCO consists of three PEG chains, each terminal of which is modified with an isocyanate (-NCO) group. The isocyanate groups in 3-Arm PEG5000-NCO can undergo rapid addition reactions with molecules containing amino (-NH2) or hydroxyl (-OH) groups to form stable carbamate or urea bonds, which can be used in applications such as constructing targeted drug delivery systems and modifying nanoparticles.

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Molecular Weight:5000 (Average)

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

3-arm PEG5000-NCO Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Biologische Aktivität

Beschreibung

In Vitro

The structure of PEG-NCO comprises two key parts that work synergistically:
Isocyanate (-NCO) group: Reacts with functional groups such as amino (-NH2) or hydroxyl (-OH) groups to form stable urea or carbamate bonds.
PEG chain: Acts as a hydrophilic spacer, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 5000 (Average)
SMILES

O=C(NCCCCCCN=C=O)OCCOCC(COCCOC(NCCCCCCN=C=O)=O)(CC)COCCOC(NCCCCCCN=C=O)=O.[n].[n].[n]
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.