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3-Hydroxypropionyl-CoA synthase

3-Hydroxypropionyl-CoA synthase (EC 6.2.1.36) catalyses a step in the 3-hydroxypropanoate/4-hydroxybutanoate cycle, an autotrophic CO2 fixation pathway found in some thermoacidophilic archaea.The enzymes from Metallosphaera sedula and Sulfolobus tokodaii can also use propionate, acrylate, acetate, and butanoate as substrates, and are thus different from EC 6.2.1.17 (propionate-CoA ligase), which does not accept acetate or butanoate.

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  • 3-Hydroxypropionyl-CoA synthase Chemical Structure
    3-Hydroxypropionyl-CoA synthase Chemical Structure
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  • 3-Hydroxypropionyl-CoA synthase