1. PROTAC
  2. PROTAC Linkers
  3. 4-Bromo-1-trimethylsilyl-1-butyne

4-Bromo-1-trimethylsilyl-1-butyne is a PROTAC linker that can be used in the synthesis of PROTACs.

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4-Bromo-1-trimethylsilyl-1-butyne

4-Bromo-1-trimethylsilyl-1-butyne Chemical Structure

CAS No. : 69361-41-7

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Description

4-Bromo-1-trimethylsilyl-1-butyne is a PROTAC linker that can be used in the synthesis of PROTACs.

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E374 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Masse moléculaire

205.17

Formule

C7H13BrSi

CAS No.
Appearance

Liquid (Density: 1.163 g/cm3)

Color

Colorless to light yellow

SMILES

BrCCC#C[Si](C)(C)C

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Pureté et documentation
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4-Bromo-1-trimethylsilyl-1-butyne Related Classifications

  • Calculateur de molarité

  • Calculateur de dilution

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nom du produit:
4-Bromo-1-trimethylsilyl-1-butyne
Cat. No.:
HY-W092986
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