4-Chloro-2-(trifluoroacetyl)aniline

Cat. No.: HY-W023836: Ficha de datos
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4-Chloro-2-(trifluoroacetyl)aniline (Compound 10), an analog of Efavirenz (HY-10572), is a Pregnane X receptor (PXR) ligand. 4-Chloro-2-(trifluoroacetyl)aniline has no PXR activation activity without induction of Cyp3a11 mRNA expression.

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4-Chloro-2-(trifluoroacetyl)aniline Estructura química

No. CAS : 154598-53-5

Tamaño	Stock	Cantidad
100 mg	En stock	Estimated Time of Arrival: December 31
250 mg	En stock	Estimated Time of Arrival: December 31
500 mg	En stock	Estimated Time of Arrival: December 31
1 g	En stock	Estimated Time of Arrival: December 31
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10 g	Obtener un presupuesto

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Descripciòn	4-Chloro-2-(trifluoroacetyl)aniline (Compound 10), an analog of Efavirenz (HY-10572), is a Pregnane X receptor (PXR) ligand. 4-Chloro-2-(trifluoroacetyl)aniline has no PXR activation activity without induction of Cyp3a11 mRNA expression^[1].
Peso molecular	223.58
Fòrmula	C₈H₅ClF₃NO
No. CAS	154598-53-5
Appearance	Solid
SMILES	O=C(C1=CC(Cl)=CC=C1N)C(F)(F)F
Envío	Room temperature in continental US; may vary elsewhere.
Almacenamiento	4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Pureza y Documentación	Ficha de datos (268 KB) SDS (252 KB) Instrucciones de manejo (2659 KB)
Referencias	[1]. Narayanan B, et al. Probing Ligand Structure-Activity Relationships in Pregnane X Receptor (PXR): Efavirenz and 8-Hydroxyefavirenz Exhibit Divergence in Activation. ChemMedChem. 2018 Apr 6;13(7):736-747. [Content Brief]