4-Pentynoyl-Coenzyme A TFA
4-Pentynoyl-Coenzyme A (4-Pentynoyl-CoA) TFA is an analog of the natural substrate acetyl-CoA (Acetyl-CoA) (HY-114293). 4-Pentynoyl-Coenzyme A TFA can replace acetyl-CoA to be recognized and utilized by lysine acetyltransferases such as p300. 4-Pentynoyl-Coenzyme A TFA can be conjugated to azide probes carrying fluorescent groups (e.g., Rhodamine-azide) or biotin (Biotin-azide) via Cu (I)-catalyzed azide-alkyne cycloaddition (CuAAC).
For research use only. We do not sell to patients.
- Formula: C28H41F3N7O19P3S
- Molecular Weight:961.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
4-Pentynoyl-Coenzyme A TFA can transfer its 4-pentynoyl group to the lysine residues of p300 protein substrates under the catalysis of p300, thereby enabling fluorescent labeling and identification via CuI-catalyzed alkyne-azide cycloaddition reaction[1].
4-Pentynoyl-Coenzyme A TFA enables fluorescent analysis and identification of p300 protein substrates and their lysine acetylation sites in in vitro cell extracts via bioorthogonal proteomic approaches[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 961.64
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Formula C28H41F3N7O19P3S
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SMILES
OC(C(F)(F)F)=O.NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](OP(O)(O)=O)[C@@H](COP(OP(OCC(C)([C@H](C(NCCC(NCCSC(CCC#C)=O)=O)=O)O)C)(O)=O)(O)=O)O3
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Synonyms
4-Pentynoyl-CoA TFA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
4-Pentynoyl-Coenzyme A TFA Related Classifications
HY-CE00983A Related Classifications
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