1. Vitamin D Related
  2. VD/VDR
  3. 5,6-trans-Vitamin D3

5,6-trans-Vitamin D3  (Synonyms: 5,6-trans-Cholecalciferol; 5,6-trans-Colecalciferol; Cholecalciferol EP Impurity A)

Cat. No.: HY-15398A Purity: 99.90%
COA Handling Instructions

5,6-trans-Vitamin D3 (5,6-trans-Cholecalciferol;5,6-trans-Colecalciferol) is a photoproduct of vitamin D3. Vitamin D3 is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.

For research use only. We do not sell to patients.

5,6-trans-Vitamin D3 Chemical Structure

5,6-trans-Vitamin D3 Chemical Structure

CAS No. : 22350-41-0

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Estimated Time of Arrival: December 31
10 mg USD 410 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

5,6-trans-Vitamin D3 (5,6-trans-Cholecalciferol;5,6-trans-Colecalciferol) is a photoproduct of vitamin D3[1]. Vitamin D3 is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.

In Vitro

Normal human keratinocytes in the cultured human keratinocytes by determining their influence on 3H-thymidine incorporation into DNA.
5,6-trans-vitamin D3 only induces significant inhibition at 10(-6) M. The dissociation constants of vitamin D receptor (VDR) for 5,6-trans-vitamin D3 is 560 nM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

384.64

Formula

C27H44O

CAS No.
SMILES

O[[email protected]@H]1C/C(C(CC1)=C)=C\C=C2[[email protected]]3([H])CC[[email protected]]([[email protected]](C)CCCC(C)C)[[email protected]@]3(C)CCC\2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

Ethyl Acetate : ≥ 50 mg/mL (129.99 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5998 mL 12.9992 mL 25.9983 mL
5 mM 0.5200 mL 2.5998 mL 5.1997 mL
10 mM 0.2600 mL 1.2999 mL 2.5998 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: 99.90%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
5,6-trans-Vitamin D3
Cat. No.:
HY-15398A
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