2. Vitamin D Related/Nuclear Receptor
  3. VD/VDR
  4. 5,6-trans-Vitamin D3

5,6-trans-Vitamin D3  (Synonyms: 5,6-trans-Cholecalciferol; 5,6-trans-Colecalciferol; Cholecalciferol EP Impurity A)

Cat. No.: HY-15398A Purity: 99.90%
COA Handling Instructions

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5,6-trans-Vitamin D3 (5,6-trans-Cholecalciferol;5,6-trans-Colecalciferol) is a photoproduct of vitamin D3. Vitamin D3 is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.

For research use only. We do not sell to patients.

5,6-trans-Vitamin D3 Chemical Structure

5,6-trans-Vitamin D3 Chemical Structure

CAS No. : 22350-41-0

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Based on 1 publication(s) in Google Scholar

5,6-trans-Vitamin D3 Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

5,6-trans-Vitamin D3 (5,6-trans-Cholecalciferol;5,6-trans-Colecalciferol) is a photoproduct of vitamin D3[1]. Vitamin D3 is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.

In Vitro

Normal human keratinocytes in the cultured human keratinocytes by determining their influence on 3H-thymidine incorporation into DNA.
5,6-trans-vitamin D3 only induces significant inhibition at 10(-6) M. The dissociation constants of vitamin D receptor (VDR) for 5,6-trans-vitamin D3 is 560 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5,6-trans-Vitamin D3 Related Antibodies
Molecular Weight

384.64

Formula

C27H44O
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O[C@@H]1C/C(C(CC1)=C)=C\C=C2[C@]3([H])CC[C@H]([C@H](C)CCCC(C)C)[C@@]3(C)CCC\2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

Ethyl Acetate : ≥ 50 mg/mL (129.99 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5998 mL 12.9992 mL 25.9983 mL
5 mM 0.5200 mL 2.5998 mL 5.1997 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.90%

COA (249 KB) HNMR (398 KB) CNMR (520 KB) RP-HPLC (315 KB) MS (421 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethyl Acetate 1 mM 2.5998 mL 12.9992 mL 25.9983 mL 64.9958 mL
5 mM 0.5200 mL 2.5998 mL 5.1997 mL 12.9992 mL
10 mM 0.2600 mL 1.2999 mL 2.5998 mL 6.4996 mL
15 mM 0.1733 mL 0.8666 mL 1.7332 mL 4.3331 mL
20 mM 0.1300 mL 0.6500 mL 1.2999 mL 3.2498 mL
25 mM 0.1040 mL 0.5200 mL 1.0399 mL 2.5998 mL
30 mM 0.0867 mL 0.4333 mL 0.8666 mL 2.1665 mL
40 mM 0.0650 mL 0.3250 mL 0.6500 mL 1.6249 mL
50 mM 0.0520 mL 0.2600 mL 0.5200 mL 1.2999 mL
60 mM 0.0433 mL 0.2167 mL 0.4333 mL 1.0833 mL
80 mM 0.0325 mL 0.1625 mL 0.3250 mL 0.8124 mL
100 mM 0.0260 mL 0.1300 mL 0.2600 mL 0.6500 mL
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5,6-trans-Vitamin D3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5,6-trans-Vitamin D322350-41-05,6-trans-Cholecalciferol 5,6-trans-ColecalciferolCholecalciferol EP Impurity AVD/VDRVitamin DVitamin D receptorphotoproductvitamin D3cell differentiationInhibitorinhibitorinhibit

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