1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. 5-Iminodaunorubicin

5-Iminodaunorubicin 

Cat. No.: HY-138645 Purity: 95.34%
Handling Instructions

5-Iminodaunorubicin is a quinone-modified anthracycline that retains antitumor activity. 5-Iminodaunorubicin produces protein-concealed DNA strand breaks in cancer cells.

For research use only. We do not sell to patients.

5-Iminodaunorubicin Chemical Structure

5-Iminodaunorubicin Chemical Structure

CAS No. : 72983-78-9

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 405 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 580 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1100 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1700 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

5-Iminodaunorubicin is a quinone-modified anthracycline that retains antitumor activity[1]. 5-Iminodaunorubicin produces protein-concealed DNA strand breaks in cancer cells[2].

In Vitro

In mouse leukemia L1210 cells, 5-Iminodaunorubicin produces protein-concealed DNA strand breaks. Many of the 5-iminodaunorubicin breaks may arise from apposed single-strand breaks (i.e., double-strand breaks)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

In rat, 5-Iminodaunorubicin (5-ID; 1-16 mg/kg) treatment produces widening of the QRS complex, increased R- and S-wave voltage, and prolonged the Q alpha T interval. And the quinone redox cycling is suppressed in 5-Iminodaunorubicin. 5-Iminodaunorubicin shows lower cardiotoxic[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

526.54

Formula

C₂₇H₃₀N₂O₉

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References
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Product Name:
5-Iminodaunorubicin
Cat. No.:
HY-138645
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