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Cat. No.: HY-W1130458

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503O8,12

503O8,12 is an ionizable cationic lipidoid that enables mRNA delivery to the spleen and lungs in mice when formulated into lipid nanoparticles with neutral helper lipid DOPE[1].

For research use only. We do not sell to patients.

CAS No.: 3067564-98-8
Formula: C₁₀₁H₂₀₀N₄O₈
Molecular Weight:1598.69

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

503O8,12 Chemical Structure

CAS No.: 3067564-98-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

503O8,12 is an ionizable cationic lipidoid that enables mRNA delivery to the spleen and lungs in mice when formulated into lipid nanoparticles with neutral helper lipid DOPE[1].

Chemical Information

CAS No. 3067564-98-8
Molecular Weight 1598.69
Formula C₁₀₁H₂₀₀N₄O₈
SMILES

O=C(CCN(CCN(CCCN(CCN(CCC(OCC(CCCCCCCCCC)CCCCCCCC)=O)CCC(OCC(CCCCCCCCCC)CCCCCCCC)=O)C)C)CCC(OCC(CCCCCCCCCC)CCCCCCCC)=O)OCC(CCCCCCCCCC)CCCCCCCC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Petersen DMS, et al. Branched-Tail Lipid Nanoparticles for Intravenous mRNA Delivery to Lung Immune, Endothelial, and Alveolar Cells in Mice. Adv Healthc Mater. 2024;13(22):e2400225. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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